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ACETYLCYSTEINE (ACETYLCYSTEINE)
- Acetaminophen overdose
- Thick bronchial secretions
- Amyloidosis
- Atelectasis due to mucous obstruction
- Bronchiectasis
- General anesthesia adjunct
- Respiratory cystic fibrosis
100 mg/mL (10 %) solution
- Inhale 6 milliliters by nebulization route 3 times per day
200 mg/mL (20 %) solution
- Inhale 3 milliliters by nebulization route 3 times per day
Acetaminophen overdose
- 140 mg/kg diluted with cola or other soft drink to a final concentration of 5% by oral route immediately, followed by 70 mg/kg by oralroute every 4 hours for 17 additional doses
Amyloidosis
- Inhale 6 milliliters by nebulization route 3 times per day
- Inhale 6 milliliters by nebulization route 4 times per day
- Inhale 10 milliliters by nebulization route 3 times per day
- Inhale 10 milliliters by nebulization route 4 times per day
- Inhale 3 milliliters by nebulization route 3 times per day
- Inhale 3 milliliters by nebulization route 4 times per day
- Inhale 5 milliliters by nebulization route 3 times per day
- Inhale 5 milliliters by nebulization route 4 times per day
Atelectasis due to mucous obstruction
- Inhale 6 milliliters by nebulization route 3 times per day
- Inhale 6 milliliters by nebulization route 4 times per day
- Inhale 10 milliliters by nebulization route 3 times per day
- Inhale 10 milliliters by nebulization route 4 times per day
- Inhale 3 milliliters by nebulization route 3 times per day
- Inhale 3 milliliters by nebulization route 4 times per day
- Inhale 5 milliliters by nebulization route 3 times per day
- Inhale 5 milliliters by nebulization route 4 times per day
Bronchiectasis
- Inhale 6 milliliters by nebulization route 3 times per day
- Inhale 6 milliliters by nebulization route 4 times per day
- Inhale 10 milliliters by nebulization route 3 times per day
- Inhale 10 milliliters by nebulization route 4 times per day
- Inhale 3 milliliters by nebulization route 3 times per day
- Inhale 3 milliliters by nebulization route 4 times per day
- Inhale 5 milliliters by nebulization route 3 times per day
- Inhale 5 milliliters by nebulization route 4 times per day
Respiratory cystic fibrosis
- Inhale 6 milliliters by nebulization route 3 times per day
- Inhale 6 milliliters by nebulization route 4 times per day
- Inhale 10 milliliters by nebulization route 3 times per day
- Inhale 10 milliliters by nebulization route 4 times per day
- Inhale 3 milliliters by nebulization route 3 times per day
- Inhale 3 milliliters by nebulization route 4 times per day
- Inhale 5 milliliters by nebulization route 3 times per day
- Inhale 5 milliliters by nebulization route 4 times per day
Thick bronchial secretions
- Inhale 6 milliliters by nebulization route 3 times per day
- Inhale 6 milliliters by nebulization route 4 times per day
- Inhale 10 milliliters by nebulization route 3 times per day
- Inhale 10 milliliters by nebulization route 4 times per day
- Inhale 3 milliliters by nebulization route 3 times per day
- Inhale 3 milliliters by nebulization route 4 times per day
- Inhale 5 milliliters by nebulization route 3 times per day
- Inhale 5 milliliters by nebulization route 4 times per day
- None
Contraindicated
- None
Severe
Moderate
- None
- Acute asthma attack
Contraindicated
- Respiratory depression
Severe
Moderate
- Esophageal varices
- Peptic ulcer
ACETYLCYSTEINE (ACETYLCYSTEINE)
- Acetaminophen overdose
- Thick bronchial secretions
- Amyloidosis
- Atelectasis due to mucous obstruction
- Bronchiectasis
- General anesthesia adjunct
- Respiratory cystic fibrosis
- None
- None
More Frequent
Severe
Less Severe
- Obstructive pulmonary disease
- Bronchial irritation
- Chest tightness
- Clammy skin
- Drowsy
- Fever
- Increased bronchial secretions
- Nausea
- Rhinorrhea
- Sore throat
- Stomatitis
- Vomiting
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Bronchospastic pulmonary disease
- Contact dermatitis
- Hemoptysis
- Urticaria
Less Severe
- None
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
None
Acetylcysteine
- Severity Level:
2
- Additional Notes: Insuff human data; consider maternal and fetal/neonatal treatment benefit
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
Acetylcysteine (inhal, Oral)
Moleculr wt low enough for excretion;No reports of toxicity with neonatal use
| General | Excretion Potential | Effect on Infant | Notes |
| No known risks; does not adversely affect lactation | Unknown | No adverse effect | Moleculr wt low enough for excretion;No reports of toxicity with neonatal use |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| Acetaminophen overdose | |
| T39.1x1A | Poisoning by 4-aminophenol derivatives, accidental (unintentional), initial encounter |
| T39.1x2A | Poisoning by 4-aminophenol derivatives, intentional self-harm, initial encounter |
| T39.1x3A | Poisoning by 4-aminophenol derivatives, assault, initial encounter |
| T39.1x4A | Poisoning by 4-aminophenol derivatives, undetermined, initial encounter |
| Amyloidosis | |
| E85 | Amyloidosis |
| E85.0 | Non-neuropathic heredofamilial amyloidosis |
| E85.1 | Neuropathic heredofamilial amyloidosis |
| E85.2 | Heredofamilial amyloidosis, unspecified |
| E85.4 | Organ-limited amyloidosis |
| E85.8 | Other amyloidosis |
| E85.81 | Light chain (Al) amyloidosis |
| E85.82 | Wild-type transthyretin-related (ATTr) amyloidosis |
| E85.89 | Other amyloidosis |
| E85.9 | Amyloidosis, unspecified |
| Atelectasis due to mucous obstruction | |
| J98.11 | Atelectasis |
| Bronchiectasis | |
| J47 | Bronchiectasis |
| J47.0 | Bronchiectasis with acute lower respiratory infection |
| J47.1 | Bronchiectasis with (acute) exacerbation |
| J47.9 | Bronchiectasis, uncomplicated |
| Q33.4 | Congenital bronchiectasis |
| Respiratory cystic fibrosis | |
| E84.0 | Cystic fibrosis with pulmonary manifestations |
| Thick bronchial secretions | |
| R09.3 | Abnormal sputum |
| 0-9 | A-Z |
|---|---|
| E84.0 | Cystic fibrosis with pulmonary manifestations |
| E85 | Amyloidosis |
| E85.0 | Non-neuropathic heredofamilial amyloidosis |
| E85.1 | Neuropathic heredofamilial amyloidosis |
| E85.2 | Heredofamilial amyloidosis, unspecified |
| E85.4 | Organ-limited amyloidosis |
| E85.8 | Other amyloidosis |
| E85.81 | Light chain (Al) amyloidosis |
| E85.82 | Wild-type transthyretin-related (ATTr) amyloidosis |
| E85.89 | Other amyloidosis |
| E85.9 | Amyloidosis, unspecified |
| J47 | Bronchiectasis |
| J47.0 | Bronchiectasis with acute lower respiratory infection |
| J47.1 | Bronchiectasis with (acute) exacerbation |
| J47.9 | Bronchiectasis, uncomplicated |
| J98.11 | Atelectasis |
| Q33.4 | Congenital bronchiectasis |
| R09.3 | Abnormal sputum |
| T39.1x1A | Poisoning by 4-aminophenol derivatives, accidental (unintentional), initial encounter |
| T39.1x2A | Poisoning by 4-aminophenol derivatives, intentional self-harm, initial encounter |
| T39.1x3A | Poisoning by 4-aminophenol derivatives, assault, initial encounter |
| T39.1x4A | Poisoning by 4-aminophenol derivatives, undetermined, initial encounter |
Formulary Reference Tool