ANDRODERM (testosterone)
- Androgen deficiency
- Gonadotropin releasing factor deficiency
- Male hypogonadism
- Bilateral anorchia
- Bilateral orchiectomy
- Chemotherapy-induced hypogonadism
- Cryptorchidism
- Klinefelter's syndrome
- Primary hypogonadism due to bilateral torsion of testes
- Primary hypogonadism due to orchitis
2 mg/24 hour transdermal 24 hour patch
- Apply 1 patch (2 mg) to clean, dry skin of the back, abdomen, and upper arms, or thighs by transdermal route once daily in the evening
4 mg/24 hr transdermal 24 hour patch
- Apply 1 patch (4 mg) to clean, dry skin of the back, abdomen, and upper arms, or thighs by transdermal route once daily in the evening
2 mg/24 hour transdermal 24 hour patch
- Apply 1 patch (2 mg) to clean, dry skin of the back, abdomen, and upper arms, or thighs by transdermal route once daily in the evening
4 mg/24 hr transdermal 24 hour patch
- Apply 1 patch (4 mg) to clean, dry skin of the back, abdomen, and upper arms, or thighs by transdermal route once daily in the evening
Androgen deficiency
- Apply 1 patch (2 mg) to clean, dry skin of the back, abdomen, and upper arms, or thighs by transdermal route once daily in the evening
- Apply 1 patch (4 mg) to clean, dry skin of the back, abdomen, and upper arms, or thighs by transdermal route once daily in the evening
Bilateral anorchia
- Apply 1 patch (2 mg) to clean, dry skin of the back, abdomen, and upper arms, or thighs by transdermal route once daily in the evening
- Apply 1 patch (4 mg) to clean, dry skin of the back, abdomen, and upper arms, or thighs by transdermal route once daily in the evening
Bilateral orchiectomy
- Apply 1 patch (2 mg) to clean, dry skin of the back, abdomen, and upper arms, or thighs by transdermal route once daily in the evening
- Apply 1 patch (4 mg) to clean, dry skin of the back, abdomen, and upper arms, or thighs by transdermal route once daily in the evening
Chemotherapy-induced hypogonadism
- Apply 1 patch (2 mg) to clean, dry skin of the back, abdomen, and upper arms, or thighs by transdermal route once daily in the evening
- Apply 1 patch (4 mg) to clean, dry skin of the back, abdomen, and upper arms, or thighs by transdermal route once daily in the evening
Cryptorchidism
- Apply 1 patch (2 mg) to clean, dry skin of the back, abdomen, and upper arms, or thighs by transdermal route once daily in the evening
- Apply 1 patch (4 mg) to clean, dry skin of the back, abdomen, and upper arms, or thighs by transdermal route once daily in the evening
Gonadotropin releasing factor deficiency
- Apply 1 patch (2 mg) to clean, dry skin of the back, abdomen, and upper arms, or thighs by transdermal route once daily in the evening
- Apply 1 patch (4 mg) to clean, dry skin of the back, abdomen, and upper arms, or thighs by transdermal route once daily in the evening
Klinefelter's syndrome
- Apply 1 patch (2 mg) to clean, dry skin of the back, abdomen, and upper arms, or thighs by transdermal route once daily in the evening
- Apply 1 patch (4 mg) to clean, dry skin of the back, abdomen, and upper arms, or thighs by transdermal route once daily in the evening
Male hypogonadism
- Apply 1 patch (2 mg) to clean, dry skin of the back, abdomen, and upper arms, or thighs by transdermal route once daily in the evening
- Apply 1 patch (4 mg) to clean, dry skin of the back, abdomen, and upper arms, or thighs by transdermal route once daily in the evening
Primary hypogonadism due to bilateral torsion of testes
- Apply 1 patch (2 mg) to clean, dry skin of the back, abdomen, and upper arms, or thighs by transdermal route once daily in the evening
- Apply 1 patch (4 mg) to clean, dry skin of the back, abdomen, and upper arms, or thighs by transdermal route once daily in the evening
Primary hypogonadism due to orchitis
- Apply 1 patch (2 mg) to clean, dry skin of the back, abdomen, and upper arms, or thighs by transdermal route once daily in the evening
- Apply 1 patch (4 mg) to clean, dry skin of the back, abdomen, and upper arms, or thighs by transdermal route once daily in the evening
- None
Contraindicated
- None
Severe
Moderate
- None
- Lactating mother
- Magnetic resonance imaging
- Malignant tumor of male breast
- Pregnancy
- Prostatic carcinoma
Contraindicated
- Acute myocardial infarction
- Cerebrovascular accident
- Chronic heart failure
- Erythrocytosis
- Hypercholesterolemia
- Kidney disease with reduction in GFR
- Polycythemia vera
- Pulmonary thromboembolism
- Venous thrombosis
Severe
Moderate
- Benign prostatic hyperplasia
- Diabetes mellitus
- Disease of liver
- Edema
- Hypertension
- Sleep apnea
ANDRODERM (testosterone)
- Androgen deficiency
- Gonadotropin releasing factor deficiency
- Male hypogonadism
- Bilateral anorchia
- Bilateral orchiectomy
- Chemotherapy-induced hypogonadism
- Cryptorchidism
- Klinefelter's syndrome
- Primary hypogonadism due to bilateral torsion of testes
- Primary hypogonadism due to orchitis
- Gynecomastia
- Priapism
- Virilism
- Menstrual disorder
- Skin irritation
More Frequent
Severe
Less Severe
- Anemia
- Benign prostatic hyperplasia
- Disease of liver
- Dizziness
- Edema
- Epididymitis
- Headache disorder
- Hypercalcemia
- Mastalgia
- Mood changes
- Nausea
- Prostatic carcinoma
- Vomiting
- Acne vulgaris
- Body fluid retention
- Contact dermatitis
- Dream disorder
- Dysgeusia
- Flu-like symptoms
- General weakness
- Hypertension
- Increased pubic hair
- Insomnia
- Libido changes
- Malaise
- Nervousness
- Pruritus of skin
- Skin swelling
- Testicular atrophy
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal hepatic function tests
- Acute myocardial infarction
- Cerebrovascular accident
- Cholestatic hepatitis
- Deep venous thrombosis
- Depression
- Drug-induced hepatitis
- Erythrocytosis
- Heart failure
- Hepatic necrosis
- Jaundice
- Malignant neoplasm of liver
- Neoplasm of liver
- Peliosis hepatis
- Pulmonary thromboembolism
- Venous thrombosis
Less Severe
- Aggressive behavior
- Alopecia
- Anorexia
- Azoospermia
- Dry skin
- Dyspnea
- Fatigue
- Hair bleaching
- Hair discoloration
- Hirsutism
- Hostility
- Hyperhidrosis
- Hyperlipidemia
- Hypoglycemic disorder
- Increased libido
- Irritability
- Memory impairment
- Nocturia
- Oligospermia
- Paresthesia
- Peripheral edema
- Sleep apnea
- Symptoms of anxiety
- Testicular pain
- Urinary hesitancy
- Urinary incontinence
- Urinary retention
- Urinary urgency
- Vasodilation of blood vessels
- Weight gain
Contraindicated
None
Severe Precaution
Testosterone (Misc. Route)
Use may not be appropriate <18 years. May cause premature epiphyseal closure.
- 1 Day – 18 Years
- Use may not be appropriate <18 years. May cause premature epiphyseal closure.
Management or Monitoring Precaution
None
Testosterone
- Severity Level:
1
- Additional Notes: Androgens contraindicated in pregnancy; risk of virilization of female fetus.
Contraindicated
Testosterone
Poss sev adv effects, premature epiphyseal closure, virilization of females
General | Excretion Potential | Effect on Infant | Notes |
Drug should not be given to breast feeding mothers | Unknown | Not known; no or inclusive data | Poss sev adv effects, premature epiphyseal closure, virilization of females |
Precaution Exists
None
General | Excretion Potential | Effect on Infant | Notes |
None |
No Known Risk
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Contraindicated
None
Precaution Exists
Testosterone
General-Avoid use in the elderly unless indicated for confirmed hypogonadism. Urogenital-Increased risk of acute kidney injury. May exacerbate prostate cancer. Cardiovascular-Reports of venous thromboembolism, deep vein thrombosis and pulmonary embolism. Possible increased risk of atrial fibrillation.
Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
Increased Risk / Adverse Effects | N | N | Y | N | N | N |
BEERS: Y HEDIS: N STOPP: Y
No Known Risk
None
- None
Androgen deficiency | |
E29.1 | Testicular hypofunction |
Bilateral anorchia | |
Q55.0 | Absence and aplasia of testis |
Chemotherapy-induced hypogonadism | |
E29.1 | Testicular hypofunction |
Cryptorchidism | |
Q53 | Undescended and ectopic testicle |
Q53.0 | Ectopic testis |
Q53.00 | Ectopic testis, unspecified |
Q53.01 | Ectopic testis, unilateral |
Q53.02 | Ectopic testes, bilateral |
Q53.1 | Undescended testicle, unilateral |
Q53.10 | Unspecified undescended testicle, unilateral |
Q53.11 | Abdominal testis, unilateral |
Q53.111 | Unilateral intraabdominal testis |
Q53.112 | Unilateral inguinal testis |
Q53.12 | Ectopic perineal testis, unilateral |
Q53.13 | Unilateral high scrotal testis |
Q53.2 | Undescended testicle, bilateral |
Q53.20 | Undescended testicle, unspecified, bilateral |
Q53.21 | Abdominal testis, bilateral |
Q53.211 | Bilateral intraabdominal testes |
Q53.212 | Bilateral inguinal testes |
Q53.22 | Ectopic perineal testis, bilateral |
Q53.23 | Bilateral high scrotal testes |
Q53.9 | Undescended testicle, unspecified |
R39.83 | Unilateral non-palpable testicle |
R39.84 | Bilateral non-palpable testicles |
Gonadotropin releasing factor deficiency | |
E23.3 | Hypothalamic dysfunction, not elsewhere classified |
Klinefelter's syndrome | |
Q98.0 | Klinefelter syndrome karyotype 47, XXY |
Q98.1 | Klinefelter syndrome, male with more than two X chromosomes |
Q98.4 | Klinefelter syndrome, unspecified |
Male hypogonadism | |
E29.1 | Testicular hypofunction |
Primary hypogonadism due to bilateral torsion of testes | |
E29.1 | Testicular hypofunction |
Primary hypogonadism due to orchitis | |
E29.1 | Testicular hypofunction |
0-9 | A-Z |
---|---|
E23.3 | Hypothalamic dysfunction, not elsewhere classified |
E29.1 | Testicular hypofunction |
E29.1 | Testicular hypofunction |
E29.1 | Testicular hypofunction |
E29.1 | Testicular hypofunction |
E29.1 | Testicular hypofunction |
Q53 | Undescended and ectopic testicle |
Q53.0 | Ectopic testis |
Q53.00 | Ectopic testis, unspecified |
Q53.01 | Ectopic testis, unilateral |
Q53.02 | Ectopic testes, bilateral |
Q53.1 | Undescended testicle, unilateral |
Q53.10 | Unspecified undescended testicle, unilateral |
Q53.11 | Abdominal testis, unilateral |
Q53.111 | Unilateral intraabdominal testis |
Q53.112 | Unilateral inguinal testis |
Q53.12 | Ectopic perineal testis, unilateral |
Q53.13 | Unilateral high scrotal testis |
Q53.2 | Undescended testicle, bilateral |
Q53.20 | Undescended testicle, unspecified, bilateral |
Q53.21 | Abdominal testis, bilateral |
Q53.211 | Bilateral intraabdominal testes |
Q53.212 | Bilateral inguinal testes |
Q53.22 | Ectopic perineal testis, bilateral |
Q53.23 | Bilateral high scrotal testes |
Q53.9 | Undescended testicle, unspecified |
Q55.0 | Absence and aplasia of testis |
Q98.0 | Klinefelter syndrome karyotype 47, XXY |
Q98.1 | Klinefelter syndrome, male with more than two X chromosomes |
Q98.4 | Klinefelter syndrome, unspecified |
R39.83 | Unilateral non-palpable testicle |
R39.84 | Bilateral non-palpable testicles |