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DOPRAM (doxapram HCl)
- Post-anesthesia respiratory depression
doxapram 20 mg/mL intravenous solution
- Dosage information is not available
20 mg/mL intravenous solution
- Dosage information is not available
- None
Contraindicated
- None
Severe
Moderate
- None
- Acute asthma attack
- Acute decompensated heart failure
- Cerebral edema
- Cerebrovascular accident
- Flail chest
- Hypoventilation
- Lower seizure threshold
- Neuromuscular blockade
- Pheochromocytoma
- Pneumothorax
- Pulmonary fibrosis
- Pulmonary thromboembolism
- Respiratory obstruction
- Seizure disorder
- Severe coronary artery disease
- Severe uncontrolled hypertension
Contraindicated
- Hyperthyroidism
- Hypotension
- Mechanical ventilation
Severe
Moderate
- Cardiac arrhythmia
- Disease of liver
- Kidney disease with reduction in GFR
- Leukopenia
DOPRAM (doxapram HCl)
- Post-anesthesia respiratory depression
- None
- None
More Frequent
Severe
Less Severe
- None
- Acute confusion
- Cough
- Diarrhea
- Dizziness
- Dysuria
- Flushing
- Headache disorder
- Hiccups
- Hyperhidrosis
- Nausea
- Vomiting
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Cardiac arrhythmia
- Chest pain
- Chest tightness
- Dyspnea
- Hemolysis
- Hypertension
- Tachycardia
- Tachypnea
- Thrombophlebitis
- Wheezing
Less Severe
- None
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
None
Doxapram Hydrochloride
- Severity Level:
B
- Additional Notes:
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Doxapram
Insufficient data available
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient data available |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Doxapram Hydrochloride
Assess risk-benefit in cardiac, hepatic, or renal impairment
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | Y | Y | N | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
| Post-anesthesia respiratory depression | |
| J95.1 | Acute pulmonary insufficiency following thoracic surgery |
| J95.2 | Acute pulmonary insufficiency following nonthoracic surgery |
| J95.82 | Postprocedural respiratory failure |
| J95.821 | Acute postprocedural respiratory failure |
| J95.822 | Acute and chronic postprocedural respiratory failure |
| 0-9 | A-Z |
|---|---|
| J95.1 | Acute pulmonary insufficiency following thoracic surgery |
| J95.2 | Acute pulmonary insufficiency following nonthoracic surgery |
| J95.82 | Postprocedural respiratory failure |
| J95.821 | Acute postprocedural respiratory failure |
| J95.822 | Acute and chronic postprocedural respiratory failure |
Formulary Reference Tool