BIJUVA (estradiol/progesterone)

Moderate

• A-hydrocort

• A-methapred

• Alagesic Lq

• amobarbital

• Amytal

• Anucort-hc

• Anusol-hc

• Aristospan Intra-articular

• Aristospan Intralesional

• Ascomp With Codeine

• Belladonna-phenobarbital

• betamethasone acet & sod phos

• Bivigam

• Brevital

• budesonide

• Bupap

• butabarbital

• Butalbital Compound W/codeine

• Butalbital Compound-codeine

• butalbital-acetaminop-caf-cod

• butalbital-acetaminophen

• butalbital-acetaminophen-caff

• butalbital-aspirin-caffeine

• Butisol

• Capacet

• Carimune Nf Nanofiltered

• Celestone Soluspan

• Cerebyx

• codeine-butalbital-ASA-caff

• Colocort

• Cortef

• Cortenema

• Cortifoam

• cortisone

• Depo-medrol

• dexamethasone

• Dexamethasone Intensol

• dexamethasone sodium phos (PF)

• dexamethasone sodium phosphate

• Dexpak 10 Day

• Dexpak 13 Day

• Dexpak 6 Day

• Dilantin

• Dilantin Extended

• Dilantin Infatabs

• Dilantin Kapseal

• Dilantin-125

• Donnatal

• Dutoprol

• Entocort Ec

• Esgic

• ethotoin

• Evista

• Ez Use Joint-tunnel-trigger

• Fioricet

• Fioricet With Codeine

• Fiorinal

• Fiorinal-codeine #3

• First-duke's

• First-mary's Mouthwash

• Flebogamma Dif

• Flo-pred

• fludrocortisone

• fosphenytoin

• Gamastan S/d

• Gammagard Liquid

• Gammagard S-d (iga < 1 Mcg/ml)

• Gammagard S/d

• Gammaked

• Gammaplex

• Gamunex-c

• Grx Hicort 25

• Hemril-30

• Hizentra

• hydrocortisone

• hydrocortisone acetate

• hydrocortisone sod succ (PF)

• hydrocortisone sod succinate

• immune glob(IgG)(hum)-maltose

• immune globulin (human) (IgG)

• immune globulin(hum),capr(IgG)

• Kenalog

• Lopressor

• Lopressor Hct

• Luminal

• Margesic

• Marten-tab

• Medrol

• Medrol (pak)

• methohexital

• methylprednisolone

• methylprednisolone acetate

• methylprednisolone sod suc(PF)

• methylprednisolone sodium succ

• methylprednisolone-bupivacaine

• metoprolol su-hydrochlorothiaz

• metoprolol succinate

• metoprolol ta-hydrochlorothiaz

• metoprolol tartrate

• Millipred

• Millipred Dp

• Mysoline

• Nembutal Sodium

• nystatin-hydrocortisone-diphen

• nystatin-TCN-HC-diphenhydramin

• Octagam

• Orapred

• Orapred Odt

• Pediapred

• Peganone

• pentobarbital sodium

• phenobarb-hyoscy-atropine-scop

• phenobarbital

• phenobarbital sodium

• Phenytek

• phenytoin

• phenytoin sodium

• phenytoin sodium extended

• Physicians Ez Use M-pred

• prednisolone

• prednisolone acetate

• prednisolone sodium phosphate

• prednisone

• Prednisone Intensol

• primidone

• Privigen

• Proctocort

• raloxifene

• Rayos

• Rectacort-hc

• secobarbital sodium

• Seconal Sodium

• Solu-cortef

• Solu-cortef (pf)

• Solu-medrol

• Solu-medrol (pf)

• Tencon

• Toprol Xl

• triamcinolone acetonide

• triamcinolone hexacetonide

• triamcinolone-lidocaine

• Uceris

• Veripred 20

• Zebutal

Moderate

• Asthma

• Depression

• Diabetes mellitus

• Edema

• Gallbladder disease

• Hepatic porphyria

• Hyperlipidemia

• Hypertension

• Hypertriglyceridemia

• Hypoparathyroidism

• Hypothyroidism

• Migraine

• Seizure disorder

• Systemic lupus erythematosus

• Unspecified lump in breast

• Uterine leiomyoma

Estradiol

• Severity Level:

  2

• Additional Notes: Not indicated during pregnancy; no known dev tox

Progesterone

• Severity Level:

  B

• Additional Notes: Insufficient human data; animal data do not suggest dev tox

Contraindicated

None

General	Excretion Potential	Effect on Infant	Notes
			None

Precaution Exists

Estradiol

Limited data indicate higher excretion may occur w/vaginal vs transderm admin

General	Excretion Potential	Effect on Infant	Notes
Evaluate use carefully	Excreted	Not known; no or inclusive data	Limited data indicate higher excretion may occur w/vaginal vs transderm admin

No Known Risk

Progesterone

Data suggest low amount excreted with no adverse effects on infants

General	Excretion Potential	Effect on Infant	Notes
No known risks; does not adversely affect lactation	Excreted	Not known; no or inclusive data	Data suggest low amount excreted with no adverse effects on infants

Contraindicated

None

Precaution Exists

Estrogenic Agents (systemic)

General-Use lowest possible dose for shortest duration and in combination with a progestin as indicated to reduce the risk of endometrial hyperplasia and breast cancer. Cardiovascular-May increase risk for thromboembolic events. Avoid use in patients with known, suspected, or history of arterial or venous thromboembolic disease. Neuro/Psych-May increase the risk for dementia. Genitourinary-May aggravate urinary incontinence.

Organ / System	HEP	REN	CARD	ENDO	NEURO / PSYCH	PULM
Increased Risk / Adverse Effects	N	N	Y	Y	N	N

BEERS: Y     HEDIS: Y     STOPP: Y

No Known Risk

None

0-9	A-Z
N95.1	Menopausal and female climacteric states
N95.9	Unspecified menopausal and perimenopausal disorder