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ANALPRAM HC (HYDROCORTISONE ACETATE/PRAMOXINE HCL)
- Hemorrhoids
- Skin inflammation
- Anal fissure
- Proctitis
- Pruritus ani
- Hydrocortisone-pramoxine Rectal Cream
- Analpram-hc Singles Rectal Cream
- Analpram-hc Rectal Cream
- Analpram-hc Lotion
- By Indication
1 %-1 % rectal cream
- Dosage information is not available
1.85 %-1.15 % rectal cream
- Dosage information is not available
2.5 %-1 % (4g) rectal cream
- Dosage information is not available
2.5 %-1 % rectal cream
- Dosage information is not available
Analpram-HC Singles 2.5 %-1 % (4g) rectal cream
- Dosage information is not available
1 %-1 % rectal cream
- Dosage information is not available
2.5 %-1 % rectal cream
- Dosage information is not available
Analpram-HC 1 %-1 % rectal cream
- Dosage information is not available
Analpram-HC 2.5 %-1 % rectal cream
- Dosage information is not available
Analpram-HC 2.5 %-1 % lotion
- Apply to the affected area(s) by topical route 3 times per day
Anal fissure
- Insert 1 applicatorful by rectal route 3 times per day
- Insert 1 applicatorful by rectal route 4 times per day
- Insert 1 applicatorful by rectal route 3-4 times daily
- Apply to the affected area(s) by topical route 3 times per day
- Apply to the affected area(s) by topical route 4 times per day
- Apply to the affected area(s) by topical route 3-4 times daily
Hemorrhoids
- Insert 1 applicatorful by rectal route 3 times per day
- Insert 1 applicatorful by rectal route 4 times per day
- Insert 1 applicatorful by rectal route 3-4 times daily
- Apply to the affected area(s) by topical route 3 times per day
- Apply to the affected area(s) by topical route 4 times per day
- Apply to the affected area(s) by topical route 3-4 times daily
Proctitis
- Insert 1 applicatorful by rectal route 3 times per day
- Insert 1 applicatorful by rectal route 4 times per day
- Insert 1 applicatorful by rectal route 3-4 times daily
- Apply to the affected area(s) by topical route 3 times per day
- Apply to the affected area(s) by topical route 4 times per day
- Apply to the affected area(s) by topical route 3-4 times daily
Pruritus ani
- Insert 1 applicatorful by rectal route 3 times per day
- Insert 1 applicatorful by rectal route 4 times per day
- Insert 1 applicatorful by rectal route 3-4 times daily
- Apply to the affected area(s) by topical route 3 times per day
- Apply to the affected area(s) by topical route 4 times per day
- Apply to the affected area(s) by topical route 3-4 times daily
Skin inflammation
- Apply to the affected area(s) by topical route 3 times per day
- Apply to the affected area(s) by topical route 4 times per day
- None
Contraindicated
- None
Severe
Moderate
- None
- Intestinal abscess
- Untreated systemic fungal infection
Contraindicated
- Active tuberculosis
- Diabetes mellitus
- Infection
- Intestinal anastomosis
- Large open wound
- Ocular herpes simplex
- Ocular hypertension
Severe
Moderate
- Chronic heart failure
- Diverticulitis of gastrointestinal tract
- Gastrointestinal fistula
- Herpes simplex infection
- Hypertension
- Hyperthyroidism
- Hypothalamic-pituitary insufficiency
- Hypothyroidism
- Kidney disease with reduction in GFR
- Measles
- Open angle glaucoma
- Osteoporosis
- Psychotic disorder
- Varicella zoster virus infection
ANALPRAM HC (HYDROCORTISONE ACETATE/PRAMOXINE HCL)
- Hemorrhoids
- Skin inflammation
- Anal fissure
- Proctitis
- Pruritus ani
- Infection
- Erythema
- Increased appetite
- Stinging of skin
More Frequent
Severe
Less Severe
- Adrenal cortical insufficiency
- Angioedema
- Dermatitis due to topical drug
- Erythema
- Folliculitis
- Hypercortisolism
- Pruritus of skin
- Purpura
- Skin and skin structure infection
- Skin atrophy
- Skin rash
- Stinging of skin
- Urticaria
- Headache disorder
- Irregular menstrual periods
- Nausea
- Paresthesia
- Pruritus of skin
- Skin rash
- Telangiectasia
- Treatment site sequelae
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abdominal distension
- Abnormal hepatic function tests
- Acute confusion
- Acute respiratory insufficiency
- Adrenal cortical insufficiency
- Anaphylaxis
- Body fluid retention
- Bradycardia
- Bullous dermatitis
- Cardiac arrhythmia
- Cataracts
- Central serous chorioretinopathy
- Chronic heart failure
- CNS toxicity
- Cyanosis
- Delirium
- Drowsy
- Drug-induced psychosis
- Dyspnea
- Excitement
- Eyelid edema
- Gastrointestinal hemorrhage
- Glaucoma
- Glycosuria
- Hallucinations
- Headache disorder
- Hepatomegaly
- Hyperglycemia
- Hypertension
- Hypotension
- Hypothalamic-pituitary insufficiency
- Idiopathic intracranial hypertension
- Impaired wound healing
- Intestinal perforation
- Methemoglobinemia
- Myopathy
- Ocular hypertension
- Osteoporosis
- Paranoid disorder
- Peptic ulcer
- Personality disorders
- Pulmonary edema
- Respiratory depression
- Seizure disorder
- Skin hypopigmentation
- Skin striae
- Skin ulcer
- Thromboembolic disorder
- Tremor
- Unconsciousness
- Urticaria
Less Severe
- Acne vulgaris
- Acneiform eruption
- Acute confusion
- Allergic dermatitis
- Alopecia
- Apprehension
- Blistering skin
- Blurred vision
- Contact dermatitis
- Depression
- Dizziness
- Dry skin
- Dyschromia
- Edema
- Euphoria
- Flushing
- Glycosuria
- Hirsutism
- Hypercortisolism
- Hyperesthesia
- Hyperglycemia
- Insomnia
- Lipodystrophy
- Miliaria
- Mood changes
- Nervousness
- Perioral dermatitis
- Rectal irritation
- Sensation of cold
- Sensation of warmth
- Skin irritation
- Sleep disorder
- Tinnitus
- Twitching
- Vomiting
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Hydrocortisone (Top,Ophth,Rect)
Prolonged or extensive use may lead to systemic absorption; may affect growth rate.
Pediatrics are more sensitive to toxic effects.
- 1 Day – 18 Years
- Prolonged or extensive use may lead to systemic absorption; may affect growth rate.
- 1 Day – 12 Years
- Prolonged or extensive use may lead to systemic absorption; may affect growth rate.
Pramoxine
Prolonged or extensive use may lead to systemic absorption; may affect growth rate.
Pediatrics are more sensitive to toxic effects.
- 1 Day – 18 Years
- Pediatrics are more sensitive to toxic effects.
- 1 Day – 12 Years
- Pediatrics are more sensitive to toxic effects.
Hydrocortisone (topical, Non-systemic)
- Severity Level:
2
- Additional Notes: Systemic absorption unknown; insuff human data
Pramoxine
- Severity Level:
C
- Additional Notes: Insufficient human data
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
Hydrocortisone (top., Rectal)
Insufficient data available; limited use may pose little risk
Per briggs, unlikely that significant amounts would be excreted in milk
| General | Excretion Potential | Effect on Infant | Notes |
| No known risks; does not adversely affect lactation | Unknown | Not known; no or inclusive data | Insufficient data available; limited use may pose little risk |
Pramoxine
Insufficient data available; limited use may pose little risk
Per briggs, unlikely that significant amounts would be excreted in milk
| General | Excretion Potential | Effect on Infant | Notes |
| No known risks; does not adversely affect lactation | Unknown | Not known; no or inclusive data | Per briggs, unlikely that significant amounts would be excreted in milk |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| Anal fissure | |
| K60.0 | Acute anal fissure |
| K60.1 | Chronic anal fissure |
| K60.2 | Anal fissure, unspecified |
| Hemorrhoids | |
| K64.0 | First degree hemorrhoids |
| K64.8 | Other hemorrhoids |
| K64.9 | Unspecified hemorrhoids |
| O22.4 | Hemorrhoids in pregnancy |
| O22.40 | Hemorrhoids in pregnancy, unspecified trimester |
| O22.41 | Hemorrhoids in pregnancy, first trimester |
| O22.42 | Hemorrhoids in pregnancy, second trimester |
| O22.43 | Hemorrhoids in pregnancy, third trimester |
| O87.2 | Hemorrhoids in the puerperium |
| Proctitis | |
| K62.7 | Radiation proctitis |
| K62.89 | Other specified diseases of anus and rectum |
| Pruritus ani | |
| L29.0 | Pruritus ani |
| L29.3 | Anogenital pruritus, unspecified |
| Skin inflammation | |
| L30.8 | Other specified dermatitis |
| L30.9 | Dermatitis, unspecified |
| 0-9 | A-Z |
|---|---|
| K60.0 | Acute anal fissure |
| K60.1 | Chronic anal fissure |
| K60.2 | Anal fissure, unspecified |
| K62.7 | Radiation proctitis |
| K62.89 | Other specified diseases of anus and rectum |
| K64.0 | First degree hemorrhoids |
| K64.8 | Other hemorrhoids |
| K64.9 | Unspecified hemorrhoids |
| L29.0 | Pruritus ani |
| L29.3 | Anogenital pruritus, unspecified |
| L30.8 | Other specified dermatitis |
| L30.9 | Dermatitis, unspecified |
| O22.4 | Hemorrhoids in pregnancy |
| O22.40 | Hemorrhoids in pregnancy, unspecified trimester |
| O22.41 | Hemorrhoids in pregnancy, first trimester |
| O22.42 | Hemorrhoids in pregnancy, second trimester |
| O22.43 | Hemorrhoids in pregnancy, third trimester |
| O87.2 | Hemorrhoids in the puerperium |
Formulary Reference Tool