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AMIODARONE HCL-D5W (AMIODARONE HCL/DEXTROSE 5 % IN WATER)
- Life-threatening ventricular tachycardia
- Ventricular fibrillation
- Prevention of ventricular fibrillation
amiodarone 150 mg/100 mL (1.5 mg/mL) in dextrose 5 % intravenous soln
- Infuse 0.5 mg/minute by continuous infusion route
amiodarone 450 mg/250 mL (1.8 mg/mL) in dextrose 5 % intravenous soln
- Dosage information is not available
amiodarone 900 mg/500 mL (1.8 mg/mL) in dextrose 5 % intravenous soln
- Infuse 0.5 mg/minute by continuous infusion route
Prevention of ventricular fibrillation
- Infuse 0.5 mg/minute by continuous infusion route
- Infuse 0.5 mg/minute by continuous infusion route for 2 weeks
- Infuse 0.5 mg/minute by continuous infusion route for 3 weeks
Ventricular fibrillation
- Infuse 0.5 mg/minute by continuous infusion route
- Infuse 0.5 mg/minute by continuous infusion route for 2 weeks
- Infuse 0.5 mg/minute by continuous infusion route for 3 weeks
- agalsidase beta
- Apokyn
- apomorphine
- Aptivus
- arsenic trioxide
- artemether-lumefantrine
- bedaquiline
- Betapace
- Betapace Af
- Caprelsa
- Celexa
- chloroquine phosphate
- chlorpromazine
- citalopram
- Coartem
- Corvert
- Crixivan
- dasatinib
- dextromethorphan-quinidine
- Diflucan
- Diskets
- disopyramide
- dofetilide
- Dolophine
- dronedarone
- droperidol
- escitalopram oxalate
- ezetimibe-simvastatin
- Fabrazyme
- fingolimod
- fluconazole
- fluconazole in dextrose(iso-o)
- fluconazole in NaCl (iso-osm)
- fosamprenavir
- Geodon
- Gilenya
- Haldol
- Haldol Decanoate
- haloperidol
- haloperidol decanoate
- haloperidol lactate
- ibutilide fumarate
- indinavir
- Invega
- Invega Sustenna
- Invirase
- isradipine
- itraconazole
- Ketek
- ketoconazole
- Lexapro
- Lexiva
- methadone
- Methadone Intensol
- Methadose
- miconazole
- Multaq
- Nebupent
- nelfinavir
- nilotinib
- Norpace
- Norpace Cr
- Norvir
- Norvir Soft Gelatin
- Noxafil
- Nuedexta
- Onmel
- Orap
- Oravig
- paliperidone
- paliperidone palmitate
- pasireotide
- Pentam
- pentamidine
- pimozide
- posaconazole
- propafenone
- quinidine gluconate
- quinidine sulfate
- ritonavir
- Rythmol
- saquinavir mesylate
- Signifor
- Sirturo
- Sorine
- sotalol
- Sotalol Af
- Sporanox
- Sporanox Pulsepak
- Sprycel
- Tasigna
- telithromycin
- Tikosyn
- tipranavir
- Trisenox
- vandetanib
- Vfend
- Vfend Iv
- Viracept
- voriconazole
- Vytorin 10-40
- Vytorin 10-80
- ziprasidone HCl
- ziprasidone mesylate
Contraindicated
- Abstral
- Actiq
- Advair Diskus
- Advair Hfa
- alfuzosin
- Aloxi
- amantadine HCl
- Anzemet
- arformoterol
- Astagraf Xl
- B cplx-C-St.Johnwrt-K.&S.ginsg
- Belladonna-phenobarbital
- Brovana
- budesonide-formoterol
- Buprenex
- buprenorphine
- buprenorphine-naloxone
- Butrans
- calcium-mag-B complex-D3-hrb61
- carbamazepine
- Carbatrol
- Cardene Iv
- Cardene Iv In Dextrose
- Cardene Iv In Sodium Chloride
- Cardene Sr
- Cardizem
- Cardizem Cd
- Cardizem La
- Cartia Xt
- Cerebyx
- clozapine
- Clozaril
- Cold & Flu Fighter
- Complera
- Coumadin
- crizotinib
- Digox
- digoxin
- Dilacor Xr
- Dilantin
- Dilantin Extended
- Dilantin Infatabs
- Dilantin Kapseal
- Dilantin-125
- Dilt-xr
- diltiazem HCl
- dolasetron
- Donnatal
- Dulera
- Duragesic
- Edurant
- Effexor Xr
- emtricitab-rilpivirine-tenofov
- Eovist
- Epitol
- Equetro
- eribulin
- ezogabine
- Fareston
- Fatigue Relief Complex
- Fazaclo
- felbamate
- Felbatol
- fentanyl
- fentanyl citrate
- fentanyl citrate (PF)
- Fentora
- flecainide
- fluticasone-salmeterol
- Foradil Aerolizer
- formoterol fumarate
- foscarnet
- Foscavir
- fosphenytoin
- gadoxetate
- granisetron
- granisetron (PF)
- Granisol
- Halaven
- Hecoria
- indapamide
- isoniazid-rifamp-pyrazinamide
- Istodax
- Jantoven
- Lanoxin
- Lanoxin Pediatric
- lapatinib
- Lazanda
- Levitra
- lithium carbonate
- lithium citrate
- Lithobid
- Luminal
- Matzim La
- moexipril
- moexipril-hydrochlorothiazide
- mometasone-formoterol
- Mysoline
- Nexavar
- nicardipine
- nicardipine in dextrose,iso-os
- nicardipine in NaCl (iso-os)
- octreotide acetate
- ondansetron
- ondansetron HCl
- ondansetron HCl (PF)
- palonosetron
- pazopanib
- Perforomist
- phenobarb-hyoscy-atropine-scop
- phenobarbital
- phenobarbital sodium
- Phenytek
- phenytoin
- phenytoin sodium
- phenytoin sodium extended
- Potiga
- primidone
- Prograf
- Qualaquin
- quetiapine
- quinine sulfate
- quinupristin-dalfopristin
- Rifadin
- Rifamate
- rifampin
- rifampin-isoniazid
- Rifater
- rilpivirine
- Risperdal
- Risperdal Consta
- Risperdal M-tab
- risperidone
- risperidone microspheres
- romidepsin
- salmeterol
- Sancuso
- Sandostatin
- Sandostatin Lar Depot
- Serevent Diskus
- Seroquel
- Seroquel Xr
- Soltamox
- sorafenib
- St. John's wort
- Sublimaze (pf)
- Suboxone
- Subsys
- Symbicort
- Synercid
- tacrolimus
- tamoxifen
- Taztia Xt
- Tegretol
- Tegretol Xr
- telavancin
- tetrabenazine
- thioridazine
- Tiazac
- tizanidine
- toremifene
- Tykerb
- Uniretic
- Univasc
- Uroxatral
- vardenafil
- vemurafenib
- venlafaxine
- Versacloz
- Vibativ
- vit C-St. John wort-elder-hb30
- Votrient
- warfarin
- Women's Complex
- Xalkori
- Xenazine
- Zanaflex
- Zelboraf
- Zofran
- Zofran Odt
- Zubsolv
- Zuplenz
Severe
Moderate
- Advicor
- Advil
- Advil Allergy Sinus
- Advil Allergy-congestion Rlf
- Advil Cold & Sinus
- Advil Congestion Relief
- Advil Liqui-gel
- Advil Migraine
- Advil Pm
- Advil Pm Liqui-gels
- Aleve
- Aleve Cold & Sinus
- Aleve Sinus & Headache
- Aleve-d Sinus & Cold
- Aleve-d Sinus & Headache
- All Day Pain Relief
- All Day Pain Relief Sinus & Co
- All Day Relief
- Altoprev
- amlodipine-atorvastatin
- Anaprox
- Anaprox Ds
- Ansaid
- Anti-diarrhea
- Anti-diarrheal (lope)-anti-gas
- Anti-diarrheal (loperamide)
- Arthrotec 50
- atazanavir
- atorvastatin
- Bystolic
- Caduet
- Caldolor
- Cambia
- Cataflam
- Celebrex
- celecoxib
- Child Ibuprofen
- Children's Advil
- Children's Ibu-drops
- Children's Ibuprofen
- Children's Medi-profen
- Children's Motrin
- Children's Profen Ib
- chlorphen-phenyleph-ibuprofen
- chlorphen-pseudoeph-ibuprofen
- Cold & Sinus Pain Relief
- Cold-sinus Relief
- cyclosporine
- cyclosporine modified
- darunavir
- Detrol
- Detrol La
- Diamode
- diclofenac epolamine
- diclofenac potassium
- diclofenac sodium
- diclofenac submicronized
- diclofenac-misoprostol
- Duexis
- Dutoprol
- Ec-naprosyn
- ethotoin
- ezetimibe-atorvastatin
- Feldene
- Flanax
- Flector
- flurbiprofen
- Gengraf
- hydrocodone-ibuprofen
- I-prin
- Ibu-drops
- Ibudone
- ibuprofen
- Ibuprofen Cold
- Ibuprofen Cold-sinus(with Pse)
- Ibuprofen Ib
- Ibuprofen Jr Strength
- ibuprofen lysine (PF)
- Ibuprofen Pm
- ibuprofen-diphenhydramine
- ibuprofen-diphenhydramine HCl
- ibuprofen-famotidine
- ibuprofen-oxycodone
- ibuprofen-phenylephrine HCl
- Imodium Multi-symptom Relief
- Inderal La
- Inderal Xl
- Infant's Ibuprofen
- Infant's Medi-profen
- Infant's Motrin
- Infants Ibu-drops
- Infants Profenib
- Innopran Xl
- Juxtapid
- Kaletra
- Lipitor
- Liptruzet
- Lo-peramide
- lomitapide
- loperamide
- loperamide-simethicone
- lopinavir-ritonavir
- Lopressor
- Lopressor Hct
- lovastatin
- Medi-profen
- Mediproxen
- meloxicam
- metoprolol su-hydrochlorothiaz
- metoprolol succinate
- metoprolol ta-hydrochlorothiaz
- metoprolol tartrate
- Mevacor
- Midol (naproxen)
- Mobic
- Motrin Ib
- Motrin Pm
- Naprelan Cr
- Naprosyn
- naproxen
- naproxen sodium
- naproxen-esomeprazole
- naproxen-pseudoephedrine
- nebivolol
- Neoprofen (ibuprofen Lysn)(pf)
- Neoral
- niacin-lovastatin
- niacin-simvastatin
- Peganone
- piroxicam
- Prezista
- procainamide
- propranolol
- propranolol-hydrochlorothiazid
- Provil
- pseudoephedrine-ibuprofen
- Rapamune
- Reprexain
- Reyataz
- rivaroxaban
- Sandimmune
- Simcor
- simvastatin
- Sinus & Cold-d
- sirolimus
- sunitinib
- Sutent
- tolterodine
- Toprol Xl
- Ultra A-d
- Vicoprofen
- Vimovo
- Voltaren-xr
- Vytorin 10-10
- Vytorin 10-20
- Wal-profen
- Wal-profen Cold-sinus
- Wal-proxen
- Xarelto
- Zipsor
- Zocor
- Zorvolex
- Bradycardia
- Cardiogenic shock
- Complete atrioventricular block
- Lactating mother
- Refractive keratoplasty by laser surgery
- Second degree atrioventricular heart block
- Sinus node dysfunction
- Syncope due to bradycardia
Contraindicated
- Alveolar hemorrhage
- Chronic pulmonary disease
- Congenital long QT syndrome
- Drug-induced hepatitis
- Eosinophilic pneumonia
- Hypersensitivity pneumonitis
- Hyperthyroidism
- Hypokalemia
- Hypomagnesemia
- Hypothyroidism
- Interstitial pneumonitis
- Optic neuritis
- Optic neuropathy
- Pregnancy
- Prolonged QT interval
- Thyrotoxicosis
- Torsades de pointes
Severe
Moderate
- Abnormal hepatic function tests
- Corneal deposits
- Disease of liver
- Invasive surgical procedure
- Peripheral neuropathy
AMIODARONE HCL-D5W (AMIODARONE HCL/DEXTROSE 5 % IN WATER)
- Life-threatening ventricular tachycardia
- Ventricular fibrillation
- Prevention of ventricular fibrillation
- Abnormal hepatic function tests
- Alveolitis
- Hypotension
- Interstitial pneumonitis
- Pulmonary fibrosis
- Skin photosensitivity
- Anorexia
- Ataxia
- Constipation
- Fatigue
- Malaise
- Nausea
- Tremor
- Vomiting
More Frequent
Severe
Less Severe
- Blurred vision
- Cardiac arrhythmia
- Chronic heart failure
- Corneal deposits
- Dyschromia
- Hyperthyroidism
- Hypothyroidism
- Optic neuritis
- Optic neuropathy
- Prolonged QT interval
- Sinus bradycardia
- Torsades de pointes
- Visual halos
- Abnormal sexual function
- Acute abdominal pain
- Dizziness
- Dry eye
- Dysgeusia
- Ecchymosis
- Flushing
- Headache disorder
- Insomnia
- Libido changes
- Paresthesia
- Photophobia
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute pancreatitis
- Acute respiratory distress syndrome
- Acute respiratory insufficiency
- Agranulocytosis
- Allergic dermatitis
- Anaphylaxis
- Angioedema
- Aplastic anemia
- Atrial fibrillation
- Atrioventricular block
- Bradycardia
- Bronchiolitis obliterans
- Bronchospastic pulmonary disease
- Bullous dermatitis
- Cholestasis
- Cholestatic hepatitis
- Corneal degeneration
- Demyelination
- DRESS syndrome
- Dyspnea
- Edema
- Eosinophilic pneumonia
- Epididymitis
- Erythema multiforme
- Exfoliative dermatitis
- Hallucinations
- Heart block
- Hemolytic anemia
- Hemoptysis
- Hepatitis
- Hypersensitivity pneumonitis
- Hypoxia
- Idiopathic intracranial hypertension
- Injection site sequelae
- Kidney disease with reduction in GFR
- Lupus-like syndrome
- Lymphadenopathy
- Malignant neoplasm of skin
- Myopathy
- Neutropenic disorder
- Pancytopenia
- Papilledema
- Parkinsonism
- Paroxysmal ventricular tachycardia
- Peripheral demyelinating neuropathy
- Peripheral neuropathy
- Pleural effusions
- Pleuritis
- Pulmonary edema
- Pulmonary hemorrhage
- Renal failure
- Rhabdomyolysis
- Scotomata
- Shock
- SIADH syndrome
- Sinus arrest
- Sinus node dysfunction
- Skin rash
- Stevens-johnson syndrome
- Thrombocytopenic disorder
- Thyroid carcinoma
- Tissue necrosis
- Toxic epidermal necrolysis
- Vasculitis
Less Severe
- Acute confusion
- Alopecia
- Back pain
- Bradykinesia
- Cough
- Delirium
- Eczema
- Eosinophilia
- Erectile dysfunction
- Facial edema
- Fever
- Gait abnormality
- Involuntary muscle movement
- Muscle spasm
- Muscle weakness
- Sialorrhea
- Sleep disorder
- Urticaria
- Xerostomia
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Amiodarone (IV)
Increased risk of hypotension, bradycardia and AV block. Safety and efficacy of IV route not established.
- 30 Days – 18 Years
- Increased risk of hypotension, bradycardia and AV block. Safety and efficacy of IV route not established.
Amiodarone
- Severity Level:
D
- Additional Notes: Incr risk of fetal adverse effects
Contraindicated
Amiodarone
Possible hypothyroidism & cv effects;Consider long t1/2 of drug(15-142 days)
| General | Excretion Potential | Effect on Infant | Notes |
| Drug should not be given to breast feeding mothers | Excreted | Not known; no or inclusive data | Possible hypothyroidism & cv effects;Consider long t1/2 of drug(15-142 days) |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Amiodarone
Cardiovascular-Risk for Torsades de pointes. Follow QTc intervals. Endocrine-Monitor for hyperthyroidism. Pulmonary-Toxicity has been reported days to weeks after drug initiation. Preexisting pulmonary disease incurs a poorer prognosis if toxicity develops. Monitor for cough and progressive dyspnea. Hepatic-Elevated hepatic transaminases are common. Neuro/Psych-Monitor for peripheral neuropathy, coordination and gait deficits. Optic neuropathy and neuritis has been reported.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | Y | Y | Y | Y | Y |
BEERS: Y HEDIS: N STOPP: Y
No Known Risk
None
- None
| Life-threatening ventricular tachycardia | |
| I47.2 | Ventricular tachycardia |
| Prevention of ventricular fibrillation | |
| I49.01 | Ventricular fibrillation |
| Ventricular fibrillation | |
| I49.01 | Ventricular fibrillation |
| 0-9 | A-Z |
|---|---|
| I47.2 | Ventricular tachycardia |
| I49.01 | Ventricular fibrillation |
| I49.01 | Ventricular fibrillation |
Formulary Reference Tool