VOQUEZNA TRIPLE PAK (vonoprazan fumarate/amoxicillin trihydrate/clarithromycin)

Moderate

• A-hydrocort

• A-methapred

• Abilify

• Abilify Discmelt

• Abilify Maintena

• Adcirca

• Adderall

• Adderall Xr

• Aerospan

• afatinib

• Altavera (28)

• Alvesco

• Alyacen 1/35 (28)

• Alyacen 7/7/7 (28)

• Ambien

• Ambien Cr

• Amethia

• Amethia Lo

• Amethyst

• aminophylline

• Amphetamine Salt Combo

• Anti-diarrhea

• Anti-diarrheal (lope)-anti-gas

• Anti-diarrheal (loperamide)

• Anucort-hc

• Anusol-hc

• Apri

• Aranelle (28)

• aripiprazole

• Aristospan Intra-articular

• Aristospan Intralesional

• Asmanex Twisthaler

• atorvastatin

• Aubra

• Aviane

• azelastine-fluticasone

• Azurette (28)

• Balziva (28)

• beclomethasone diprop (AQ)

• beclomethasone dipropionate

• Beconase Aq

• betamethasone acet & sod phos

• Beyaz

• Breo Ellipta

• Brevicon (28)

• Briellyn

• budesonide

• budesonide-formoterol

• Burn Calories

• buspirone

• Camila

• Camrese

• Camrese Lo

• Caziant (28)

• Celestone Soluspan

• Chateal

• Cialis

• ciclesonide

• cilostazol

• cinacalcet

• Colocort

• Cortef

• Cortenema

• Cortifoam

• cortisone

• Cryselle (28)

• Cyclafem 1/35 (28)

• Cyclafem 7/7/7 (28)

• Cyclessa (28)

• Daily Energy

• darifenacin

• Dasetta 1/35 (28)

• Dasetta 7/7/7 (28)

• Daysee

• Depo-medrol

• Depo-provera

• Depo-subq Provera 104

• desog-e.estradiol/e.estradiol

• Desogen

• desogestrel-ethinyl estradiol

• Detrol

• dexamethasone

• Dexamethasone Intensol

• dexamethasone sodium phos (PF)

• dexamethasone sodium phosphate

• Dexedrine Spansule

• Dexpak 10 Day

• Dexpak 13 Day

• Dexpak 6 Day

• dextroamphetamine

• dextroamphetamine-amphetamine

• Diabeta

• Diamode

• Dietex Forte

• drospirenone-e.estradiol-lm.FA

• drospirenone-ethinyl estradiol

• Dulera

• Dymista

• Edluar

• Elinest

• Elixophyllin

• Emoquette

• Enablex

• Enpresse

• Enskyce

• Entocort Ec

• Errin

• Estarylla

• estradiol valerate-dienogest

• Estrostep Fe-28

• eszopiclone

• ethynodiol diac-eth estradiol

• etonogestrel

• etonogestrel-ethinyl estradiol

• Etopophos

• etoposide

• etoposide phosphate

• Ez Use Joint-tunnel-trigger

• ezetimibe-atorvastatin

• Falmina (28)

• Femcon Fe

• fesoterodine

• Fetzima

• fingolimod

• First-duke's

• First-mary's Mouthwash

• Flo-pred

• Flonase

• Flovent Diskus

• Flovent Hfa

• fludrocortisone

• flunisolide

• fluticasone

• fluticasone furoate

• fluticasone-vilanterol

• Generess Fe

• Gianvi (28)

• Gildagia

• Gildess

• Gildess Fe

• Gilenya

• Gilotrif

• glipizide

• glipizide-metformin

• Glucotrol

• Glucotrol Xl

• Glucovance

• glyburide

• glyburide micronized

• glyburide-metformin

• Glynase

• Grx Hicort 25

• Guarana

• guarana-calcium-amino acid cmb

• guarana-calcium-phosphorus

• guarana-Cr-citaurantium-hrb109

• guarana-Cr-gr tea-yrb mat-hb39

• Heather

• Hemril-30

• hydrocortisone

• hydrocortisone acetate

• hydrocortisone sod succ (PF)

• hydrocortisone sod succinate

• Imodium Multi-symptom Relief

• Intermezzo

• Introvale

• ivacaftor

• Jencycla

• Jolessa

• Jolivette

• Junel 1.5/30 (21)

• Junel 1/20 (21)

• Junel Fe 1.5/30 (28)

• Junel Fe 1/20 (28)

• Kalydeco

• Kariva (28)

• Kelnor 1/35 (28)

• Kenalog

• Kurvelo

• L norgest&E estradiol-E estrad

• Larin 1/20 (21)

• Larin Fe

• Leena 28

• Lessina

• levomilnacipran

• Levonest (28)

• levonorg-eth estrad triphasic

• levonorgestrel

• levonorgestrel-ethinyl estrad

• Levora 0.15/30 (28)

• Levora-28

• Lipitor

• Liptruzet

• Livalo

• Lo Loestrin Fe

• Lo-peramide

• Loestrin 1.5/30 (21)

• Loestrin 1/20 (21)

• Loestrin Fe 1.5/30 (28)

• Loestrin Fe 1/20 (28)

• Lomedia 24 Fe

• loperamide

• loperamide-simethicone

• Loryna (28)

• Loseasonique

• Low-ogestrel (28)

• Lunesta

• Lutera (28)

• Lyza

• Marlissa

• Medrol

• Medrol (pak)

• medroxyprogesterone

• methylprednisolone

• methylprednisolone acetate

• methylprednisolone sod suc(PF)

• methylprednisolone sodium succ

• methylprednisolone-bupivacaine

• Microgestin 1.5/30 (21)

• Microgestin 1/20 (21)

• Microgestin Fe 1.5/30 (28)

• Microgestin Fe 1/20 (28)

• midazolam

• midazolam (PF)

• Millipred

• Millipred Dp

• Minastrin 24 Fe

• Mircette (28)

• Modicon (28)

• mometasone

• mometasone-formoterol

• Mono-linyah

• Mononessa (28)

• mv,Ca,Fe,min-FA-guarana-caff

• mv,Ca,Fe,min-FA-hrb cmplx145

• mv,Ca,Fe,min-FA-hrb cmplx146

• mv,Ca,min-iron-FA-guarana-caff

• My Way

• Myzilra

• Nasacort

• Nasacort Aq

• Nasonex

• Natazia

• Necon 0.5/35 (28)

• Necon 1/35 (28)

• Necon 1/50 (28)

• Necon 10/11 (28)

• Necon 7/7/7 (28)

• Nexplanon

• Next Choice One Dose

• Nor-qd

• Nora-be

• norelgestrom-ethinyl estradiol

• noreth-ethinyl estradiol-iron

• norethin-e.estradiol triphasic

• norethin-eth estrad biphasic

• norethindrone (contraceptive)

• norethindrone ac-eth estradiol

• norethindrone-e.estradiol-iron

• norethindrone-ethin estradiol

• norethindrone-mestranol

• norgestimate-ethinyl estradiol

• norgestrel-ethinyl estradiol

• Norinyl 1+35 (28)

• Norinyl 1+50 (28)

• Nortrel 0.5/35 (28)

• Nortrel 1/35 (21)

• Nortrel 1/35 (28)

• Nortrel 7/7/7 (28)

• Nuvaring

• nystatin-hydrocortisone-diphen

• nystatin-TCN-HC-diphenhydramin

• Ocella

• Ogestrel (28)

• Omnaris

• One Daily

• One Daily Energy

• One Daily Healthy Weight

• One Daily Women's Metabolism

• One-a-day Weightsmart

• One-a-day Women's Active

• Onglyza

• Orapred

• Orapred Odt

• Orsythia

• Ortho Evra

• Ortho Micronor

• Ortho Tri-cyclen (28)

• Ortho Tri-cyclen Lo (28)

• Ortho-cept (28)

• Ortho-cyclen (28)

• Ortho-novum 1/35 (28)

• Ortho-novum 7/7/7 (28)

• Ovcon-35 (28)

• Pediapred

• Philith

• Physicians Ez Use M-pred

• Pimtrea (28)

• Pirmella

• pitavastatin

• Plan B One-step

• Pletal

• Portia

• Prandimet

• Prandin

• Pravachol

• pravastatin

• prednisolone

• prednisolone acetate

• prednisolone sodium phosphate

• prednisone

• Prednisone Intensol

• Previfem

• probenecid

• Procentra

• Proctocort

• Pulmicort

• Pulmicort Flexhaler

• Qnasl

• Quartette

• Quasense

• Qvar

• Rayos

• Reclipsen (28)

• Rectacort-hc

• regorafenib

• repaglinide

• repaglinide-metformin

• Revatio

• Rhinocort Aqua

• Safyral

• saxagliptin

• Seasonique

• Sensipar

• sildenafil

• solifenacin

• Solu-cortef

• Solu-cortef (pf)

• Solu-medrol

• Solu-medrol (pf)

• Sprintec (28)

• Sronyx

• Stivarga

• Syeda

• Symbicort

• tadalafil

• Theo-24

• Theochron

• theophylline

• theophylline in dextrose 5 %

• Tilia Fe

• Toposar

• Toviaz

• Tri-estarylla

• Tri-legest Fe

• Tri-linyah

• Tri-norinyl (28)

• Tri-previfem (28)

• Tri-sprintec (28)

• triamcinolone acetonide

• triamcinolone hexacetonide

• triamcinolone-lidocaine

• triazolam

• Trinessa (28)

• Trivora (28)

• Uceris

• Ultra A-d

• Ultra Energy

• Velivet Triphasic Regimen (28)

• Veramyst

• Veripred 20

• Vesicare

• Vestura (28)

• Viagra

• Viorele (28)

• Vyfemla (28)

• Wera (28)

• Women's Active

• Wymzya Fe

• Yasmin (28)

• Yaz 28

• Zarah

• Zenchent (28)

• Zenchent Fe

• Zenzedi

• Zeosa

• Zetonna

• zolpidem

• Zolpimist

• Zovia 1/35E (28)

• Zovia 1/50E (28)

Moderate

• Bradycardia

• Kidney disease with likely reduction in GFR

• Myasthenia gravis

Amoxicillin

• Severity Level:

  2

• Additional Notes: Insufficient human data available on developmental toxicity risk.

Clarithromycin

• Severity Level:

  2

• Additional Notes: Available human data suggest developmental toxicity risk is low

Vonoprazan

• Severity Level:

  2

• Additional Notes: Mfg does not recommend, insufficient data available

Contraindicated

Vonoprazan

Mfr recs to avoid breastfeeding during therapy and 2 days after therapy ends.

General	Excretion Potential	Effect on Infant	Notes
Drug should not be given to breast feeding mothers	Unknown	Not known; no or inclusive data	Mfr recs to avoid breastfeeding during therapy and 2 days after therapy ends.

Precaution Exists

Amoxicillin

May cause sensitization, diarrhea or rash in nursing infant.

Low amount excreted unlikely to affect nursing infant;Monitor for diarrhea

General	Excretion Potential	Effect on Infant	Notes
Evaluate use carefully	Excreted	Drug shown to have adverse effect	May cause sensitization, diarrhea or rash in nursing infant.

Clarithromycin

May cause sensitization, diarrhea or rash in nursing infant.

Low amount excreted unlikely to affect nursing infant;Monitor for diarrhea

General	Excretion Potential	Effect on Infant	Notes
Evaluate use carefully	Excreted	Not known; no or inclusive data	Low amount excreted unlikely to affect nursing infant;Monitor for diarrhea

No Known Risk

None

General	Excretion Potential	Effect on Infant	Notes
			None

Contraindicated

None

Precaution Exists

Amoxicillin

Renal-May need to adjust dosage for renal impairment.

Renal-May require dosage adjustment with severe renal impairment to minimize risk of QT-prolongation. Cardiovascular-Contraindicated in patients with pre-existing QT prolongation. Elderly may be more susceptible to Torsades de Pointes.

Organ / System	HEP	REN	CARD	ENDO	NEURO / PSYCH	PULM
Increased Risk / Adverse Effects	Y	N	N	N	N	N

BEERS: N     HEDIS: N     STOPP: N

Clarithromycin

Renal-May need to adjust dosage for renal impairment.

Renal-May require dosage adjustment with severe renal impairment to minimize risk of QT-prolongation. Cardiovascular-Contraindicated in patients with pre-existing QT prolongation. Elderly may be more susceptible to Torsades de Pointes.

Organ / System	HEP	REN	CARD	ENDO	NEURO / PSYCH	PULM
Increased Risk / Adverse Effects	Y	Y	N	N	N	N

BEERS: N     HEDIS: N     STOPP: N

No Known Risk

None

0-9	A-Z
B96.81	Helicobacter pylori [h. pylori] as the cause of diseases classified elsewhere
B96.81	Helicobacter pylori [h. pylori] as the cause of diseases classified elsewhere