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ULTIVA (REMIFENTANIL HCL)
- General anesthesia adjunct
- Local anesthesia adjunct
- Postoperative acute pain
1 mg intravenous solution
- Infuse 0.025 mcg/kg/minute by continuous infusion route
2 mg intravenous solution
- Infuse 0.025 mcg/kg/minute by continuous infusion route
5 mg intravenous solution
- Infuse 0.025 mcg/kg/minute by continuous infusion route
1 mg intravenous solution
- Infuse 0.025 mcg/kg/minute by continuous infusion route
2 mg intravenous solution
- Infuse 0.025 mcg/kg/minute by continuous infusion route
5 mg intravenous solution
- Infuse 0.025 mcg/kg/minute by continuous infusion route
remifentanil 1 mg intravenous solution
- Infuse 0.025 mcg/kg/minute by continuous infusion route
remifentanil 2 mg intravenous solution
- Infuse 0.025 mcg/kg/minute by continuous infusion route
remifentanil 5 mg intravenous solution
- Infuse 0.025 mcg/kg/minute by continuous infusion route
General anesthesia adjunct
- Infuse 0.05 mcg/kg/minute by continuous infusion route
- Infuse 0.1 mcg/kg/minute by continuous infusion route
- Infuse 2 mcg/kg/minute by continuous infusion route
Local anesthesia adjunct
- Infuse 0.05 mcg/kg/minute by continuous infusion route
- Infuse 0.1 mcg/kg/minute by continuous infusion route
- Infuse 2 mcg/kg/minute by continuous infusion route
Postoperative acute pain
- Infuse 0.025 mcg/kg/minute by continuous infusion route
- Infuse 0.1 mcg/kg/minute by continuous infusion route
- Infuse 0.2 mcg/kg/minute by continuous infusion route
- Depade
- naltrexone
- naltrexone microspheres
- Revia
- Vivitrol
Contraindicated
- Azilect
- Eldepryl
- isocarboxazid
- linezolid
- Marplan
- Matulane
- methylene blue (antidote)
- Nardil
- Parnate
- phenelzine
- procarbazine
- rasagiline
- selegiline HCl
- sodium oxybate
- tranylcypromine
- Xyrem
- Zelapar
- Zyvox
Severe
Moderate
- Buprenex
- buprenorphine
- buprenorphine-naloxone
- butorphanol tartrate
- Butrans
- Fanatrex
- gabapentin
- gabapentin enacarbil
- Gralise
- Gralise 30-day Starter Pack
- Horizant
- nalbuphine
- Neurontin
- Suboxone
- Zubsolv
- None
Contraindicated
- Drug abuse
- History of opioid overdose
- Hypotension
Severe
Moderate
- Acute pancreatitis
- Adrenal cortical insufficiency
- Bradycardia
- Respiratory depression
- Seizure disorder
ULTIVA (REMIFENTANIL HCL)
- General anesthesia adjunct
- Local anesthesia adjunct
- Postoperative acute pain
- Bradycardia
- Hypotension
- Muscle rigidity
- Respiratory depression
- Headache disorder
- Nausea
- Vomiting
More Frequent
Severe
Less Severe
- Hypertension
- Chills
- Fever
- Tachycardia
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal hepatic function tests
- Agitation
- Anaphylaxis
- Anemia
- Apnea
- Biliary spasm
- Cardiac arrhythmia
- Ileus
- Leukocytosis
- Lymphopenia
- Thrombocytopenic disorder
Less Severe
- Acute confusion
- Constipation
- Diarrhea
- Dysphoric mood
- Erythema
- Gastroesophageal reflux disease
- Hyperglycemia
- Hyperhidrosis
- Non-cardiac chest pain
- Pruritus of skin
- Skin rash
- Symptoms of anxiety
- Urinary retention
- Urticaria
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
None
Remifentanil
- Severity Level:
2
- Additional Notes: Neonatal withdrawal/resp.depress. w/chronic or high dose
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Remifentanil
Fentanyl analogs excreted in human milk; short half life;Adv effects unlikely
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Fentanyl analogs excreted in human milk; short half life;Adv effects unlikely |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Remifentanil
General-Elderly more susceptible to toxicity, therefore starting dose should be 50% of normal adult dose. General-Consider naloxone order to mitigate accidental overdose.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | N | Y | Y | N | N |
BEERS: Y HEDIS: N STOPP: N
No Known Risk
None
- None
| Postoperative acute pain | |
| G89.12 | Acute post-thoracotomy pain |
| G89.18 | Other acute postprocedural pain |
| 0-9 | A-Z |
|---|---|
| G89.12 | Acute post-thoracotomy pain |
| G89.18 | Other acute postprocedural pain |
Formulary Reference Tool