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ACTIMMUNE (INTERFERON GAMMA-1B,RECOMB.)
- Chronic granulomatous disease
- Infantile malignant osteopetrosis
100 mcg (2 million unit)/0.5 mL subcutaneous solution
- Dosage information is not available
100 mcg (2 million unit)/0.5 mL subcutaneous solution
- Dosage information is not available
- adenovirus vac live type-4 & 7
- adenovirus vaccine live type-4
- adenovirus vaccine live type-7
- BCG vaccine, live (PF)
- flu vac,qval 2013-14 (2-49yrs)
- Flumist 2013-2014
- M-m-r Ii (pf)
- measles,mumps&rubella vacc(PF)
- measles,mumps,rub,varicel(PF)
- natalizumab
- Proquad (pf)
- Rotateq Vaccine
- rotavirus vaccine live, penta
- typhoid vaccine
- Tysabri
- varicella virus vacc live (PF)
- Varivax (pf)
- Vivotif Berna Vaccine
- yellow fever vaccine live (PF)
- Yf-vax (pf)
- Zostavax (pf)
- zoster vaccine live (PF)
Contraindicated
- clozapine
- Clozaril
- deferiprone
- Droxia
- Fazaclo
- Ferriprox
- Hydrea
- hydroxyurea
- Versacloz
Severe
Moderate
- None
- None
Contraindicated
- Abnormal hepatic function tests
- Acute myocardial infarction
- Bone marrow depression
- Cardiac arrhythmia
- Chronic heart failure
- Disease of liver
- Myocardial ischemia
- Neutropenic disorder
- Seizure disorder
- Thrombocytopenic disorder
Severe
Moderate
- Kidney disease with reduction in GFR
- Lupus-like syndrome
ACTIMMUNE (INTERFERON GAMMA-1B,RECOMB.)
- Chronic granulomatous disease
- Infantile malignant osteopetrosis
- None
- Chills
- Diarrhea
- Fatigue
- Fever
- Flu-like symptoms
- Headache disorder
- Injection site sequelae
- Nausea
- Skin rash
- Vomiting
More Frequent
Severe
Less Severe
- None
- Arthralgias
- Dizziness
- Gait abnormality
- Myalgias
- Weight loss
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal hepatic function tests
- Acute myocardial infarction
- Acute renal failure
- Angina
- Atrial fibrillation
- Atrioventricular block
- Bronchospastic pulmonary disease
- Cardiac arrhythmia
- Chronic heart failure
- CNS toxicity
- Colitis
- Deep venous thrombosis
- Disease of liver
- Gastrointestinal hemorrhage
- Heart block
- Hepatomegaly
- Hyperglycemia
- Hypersensitivity drug reaction
- Hypokalemia
- Hyponatremia
- Hypotension
- Interstitial pneumonitis
- Leukopenia
- Lupus-like syndrome
- Myocardial ischemia
- Nephrotoxicity
- Neutropenic disorder
- Pancreatitis
- Pulmonary edema
- Pulmonary thromboembolism
- Seizure disorder
- Stevens-johnson syndrome
- Tachypnea
- Thrombocytopenic disorder
- Transient cerebral ischemia
Less Severe
- Acute abdominal pain
- Acute confusion
- Altered mental status
- Atopic dermatitis
- Back pain
- Chest discomfort
- Depression
- Dyspepsia
- General weakness
- Hallucinations
- Hypertriglyceridemia
- Malaise
- Muscle spasm
- Proteinuria
- Syncope
- Tachycardia
- Upper respiratory infection
- Urticaria
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Interferon gamma-1b
Reports of increased liver enzymes, and rare hepatomegaly, Stevens-Johnson syndrome, granulomatous colitis, atopic dermatitis.
- 1 Day – 3 Years
- Reports of increased liver enzymes, and rare hepatomegaly, Stevens-Johnson syndrome, granulomatous colitis, atopic dermatitis.
Interferon Gamma-1B
- Severity Level:
2
- Additional Notes: Insufficient human data; no dev tox in animals at 100 x the mrhd
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Interferon Gamma-1B
No data available
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | No data available |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| Chronic granulomatous disease | |
| D71 | Functional disorders of polymorphonuclear neutrophils |
| Infantile malignant osteopetrosis | |
| Q78.2 | Osteopetrosis |
| 0-9 | A-Z |
|---|---|
| D71 | Functional disorders of polymorphonuclear neutrophils |
| Q78.2 | Osteopetrosis |
Formulary Reference Tool