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PRECEDEX (DEXMEDETOMIDINE HCL)
- Sedation in intubated patient
- Sedation as adjunct to anesthesia
- Precedex Intravenous Solution
- Precedex In 0.9 % Sodium Chloride Intravenous Solution
- Dexmedetomidine Intravenous Solution
- Dexmedetomidine In 0.9 % Sodium Chloride Intravenous Soln
100 mcg/mL intravenous solution
- Dosage information is not available
200 mcg/50 mL (4 mcg/mL) in 0.9 % sodium chloride IV solution
- Dosage information is not available
400 mcg/100 mL (4 mcg/mL) in 0.9% sodium chloride IV solution
- Dosage information is not available
80 mcg/20 mL (4 mcg/mL) in 0.9 % sodium chloride IV solution
- Dosage information is not available
100 mcg/mL intravenous solution
- Dosage information is not available
dexmedetomidine 100 mcg/mL intravenous solution
- Dosage information is not available
dexmedetomidine 200 mcg/50 mL (4 mcg/mL) in 0.9 % sodium chloride IV
- Dosage information is not available
dexmedetomidine 400 mcg/100 mL (4 mcg/mL) in 0.9 % sodium chloride IV
- Dosage information is not available
dexmedetomidine 80 mcg/20 mL (4 mcg/mL) in 0.9 % sodium chloride IV
- Dosage information is not available
- None
Contraindicated
- None
Severe
Moderate
- Betapace
- Betapace Af
- Sorine
- sotalol
- Sotalol Af
- None
Contraindicated
- Bradycardia
- Disease of liver
- Hypotension
- Hypovolemia
- Severe chronic heart failure
- Severe heart block
Severe
Moderate
- None
PRECEDEX (DEXMEDETOMIDINE HCL)
- Sedation in intubated patient
- Sedation as adjunct to anesthesia
- Hypotension
- Hypoxia
- Xerostomia
More Frequent
Severe
Less Severe
- Acute renal failure
- Atrial fibrillation
- Bradycardia
- Hyperglycemia
- Hypertension
- Hypokalemia
- Hypomagnesemia
- Pleural effusions
- Pulmonary edema
- Constipation
- Fever
- Nausea
- Peripheral edema
- Symptoms of anxiety
- Vomiting
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acidosis
- Acute confusion
- Acute respiratory distress syndrome
- Agitation
- Anemia
- Apnea
- Atrioventricular block
- Bronchospastic pulmonary disease
- Delirium
- Dyspnea
- Extrasystoles
- Hallucinations
- Heart block
- Hemorrhage
- Hypercapnia
- Hyperkalemia
- Hypernatremia
- Oliguria
- Prolonged QT interval
- Pulmonary congestion
- Respiratory acidosis
- Respiratory depression
- Seizure disorder
- Sinus arrest
- Supraventricular tachycardia
- Ventricular arrhythmias
- Ventricular tachycardia
Less Severe
- Acute abdominal pain
- Dizziness
- Dysphasia
- Headache disorder
- Hyperhidrosis
- Neuralgia
- Pain
- Photopsia
- Polydipsia
- Polyuria
- Visual changes
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Dexmedetomidine
Safety and efficacy not established in pediatrics for procedural or ICU sedation.
- 1 Day – 18 Years
- Safety and efficacy not established in pediatrics for procedural or ICU sedation.
Dexmedetomidine Hydrochloride
- Severity Level:
2
- Additional Notes: Insuff human data; crosses placenta; animal data sug dev tox
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Dexmedetomidine
Insufficient data available
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient data available |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Dexmedetomidine (intravenous)
Cardiovascular-Increased incidence of hypotension and bradycardia. A reduced loading dose of 0.5 mcg/kg given over 10 minutes is recommended and a reduction in the maintenance infusion should be considered.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | Y | Y | N | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
Formulary Reference Tool