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VALCHLOR (mechlorethamine HCl)
- Mycosis fungoides
0.016 % topical gel
- Apply a thin layer to completely dry skin by topical route once dailyat least 4 hours before or 30 mins after showering or washing
Mycosis fungoides
- Apply a thin layer to completely dry skin by topical route once dailyat least 4 hours before or 30 mins after showering or washing
- None
Contraindicated
- None
Severe
Moderate
- None
- Lactating mother
Contraindicated
- Basal cell carcinoma of skin
- Pregnancy
- Squamous cell carcinoma
Severe
Moderate
- None
VALCHLOR (mechlorethamine HCl)
- Mycosis fungoides
- None
- Dermatitis due to topical drug
- Pruritus of skin
More Frequent
Severe
Less Severe
- Anemia
- Neutropenic disorder
- Thrombocytopenic disorder
- Bacterial skin and skin structure infection
- Skin pigmentation enhancement
- Skin ulcer
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Anaphylaxis
Less Severe
- Basal cell carcinoma of skin
- Squamous cell carcinoma
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Mechlorethamine (topical)
Safety and efficacy not established.
- 1 Day – 18 Years
- Safety and efficacy not established.
Mechlorethamine
- Severity Level:
D
- Additional Notes: Case reports of developmental toxicity with systemic exposure
Contraindicated
Mechlorethamine
Molecular weight low enough for possible excretion; drug is carcinogenic
| General | Excretion Potential | Effect on Infant | Notes |
| Drug should not be given to breast feeding mothers | Unknown | Not known; no or inclusive data | Molecular weight low enough for possible excretion; drug is carcinogenic |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| Mycosis fungoides | |
| C84.0 | Mycosis fungoides |
| C84.00 | Mycosis fungoides, unspecified site |
| C84.01 | Mycosis fungoides, lymph nodes of head, face, and neck |
| C84.02 | Mycosis fungoides, intrathoracic lymph nodes |
| C84.03 | Mycosis fungoides, intra-abdominal lymph nodes |
| C84.04 | Mycosis fungoides, lymph nodes of axilla and upper limb |
| C84.05 | Mycosis fungoides, lymph nodes of inguinal region and lower limb |
| C84.06 | Mycosis fungoides, intrapelvic lymph nodes |
| C84.07 | Mycosis fungoides, spleen |
| C84.08 | Mycosis fungoides, lymph nodes of multiple sites |
| C84.09 | Mycosis fungoides, extranodal and solid organ sites |
| 0-9 | A-Z |
|---|---|
| C84.0 | Mycosis fungoides |
| C84.00 | Mycosis fungoides, unspecified site |
| C84.01 | Mycosis fungoides, lymph nodes of head, face, and neck |
| C84.02 | Mycosis fungoides, intrathoracic lymph nodes |
| C84.03 | Mycosis fungoides, intra-abdominal lymph nodes |
| C84.04 | Mycosis fungoides, lymph nodes of axilla and upper limb |
| C84.05 | Mycosis fungoides, lymph nodes of inguinal region and lower limb |
| C84.06 | Mycosis fungoides, intrapelvic lymph nodes |
| C84.07 | Mycosis fungoides, spleen |
| C84.08 | Mycosis fungoides, lymph nodes of multiple sites |
| C84.09 | Mycosis fungoides, extranodal and solid organ sites |
Formulary Reference Tool