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EPIPEN (EPINEPHRINE)
- Anaphylaxis
- Epipen Injection,auto-injector
- Epipen Im Injector
- Epipen 2-pak Injection,auto-injector
- Epipen 2-pak Im Pen Injector
- Epinephrine Injection,auto-injector
- Epinephrine Im Pen Injector
- Auvi-q Injection,auto-injector
- By Indication
EpiPen 0.3 mg/0.3 mL injection, auto-injector
- Inject 0.3 milliliter (0.3 mg) by intramuscular route once as needed for anaphylaxis
0.3 mg/0.3 mL injection, auto-injector
- Inject 0.3 milliliter (0.3 mg) by intramuscular route once as needed for anaphylaxis
2-Pak 0.3 mg/0.3 mL injection, auto-injector
- Inject 0.3 milliliter (0.3 mg) by intramuscular route once as needed for anaphylaxis
2-Pak 0.3 mg/0.3 mL injection, auto-injector
- Inject 0.3 milliliter (0.3 mg) by intramuscular route once as needed for anaphylaxis
(Jr) 0.15 mg/0.3 mL injection,auto-injector
- Dosage information is not available
0.1 mg/0.1 mL injection, auto-injector
- Dosage information is not available
0.15 mg/0.15 mL auto-injector (for 33 to 66 lb patients)
- Dosage information is not available
0.3 mg/0.3 mL injection, auto-injector
- Inject 0.3 milliliter (0.3 mg) by intramuscular route once as needed for anaphylaxis
(Jr) 0.15 mg/0.3 mL injection,auto-injector
- Dosage information is not available
0.1 mg/0.1 mL injection, auto-injector
- Dosage information is not available
0.15 mg/0.15 mL auto-injector (for 33 to 66 lb patients)
- Dosage information is not available
0.3 mg/0.3 mL injection, auto-injector
- Inject 0.3 milliliter (0.3 mg) by intramuscular route once as needed for anaphylaxis
0.1 mg/0.1 mL injection,auto-injector
- Dosage information is not available
0.15 mg/0.15 mL auto-injector (for 33 lb to 66 lb patients)
- Dosage information is not available
0.3 mg/0.3 mL injection, auto-injector
- Inject 0.3 milliliter (0.3 mg) by intramuscular route once as needed for anaphylaxis
Anaphylaxis
- Inject 0.3 milliliter (0.3 mg) by intramuscular route once as needed for anaphylaxis
- Inject 0.3 milliliter (0.3 mg) by intramuscular route once
- None
Contraindicated
- None
Severe
Moderate
- None
- None
Contraindicated
- Acute myocardial infarction
- Angina
- Angle-closure glaucoma
- Cardiac arrhythmia
- Cardiogenic shock
- Cerebral arteriosclerosis
- Congenital long QT syndrome
- Coronary artery disease
- Dilated cardiomyopathy
- Hemorrhagic shock
- Hypertension
- Hyperthyroidism
- Sinus tachycardia
Severe
Moderate
- Diabetes mellitus
- Parkinsonism
EPIPEN (EPINEPHRINE)
- Anaphylaxis
- None
- Dizziness
- General weakness
- Headache disorder
- Nervousness
- Pallor
- Palpitations
- Symptoms of anxiety
- Tachycardia
- Tremor
More Frequent
Severe
Less Severe
- None
- Hypertension
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute myocardial infarction
- Administration site infection
- Angina
- Cardiac arrhythmia
- Cardiomyopathy
- Cerebrovascular accident
- Chest pain
- Extravasation injury
- Gangrene
- Hyperglycemia
- Hypoglycemic disorder
- Hypokalemia
- Intracranial bleeding
- Kidney disease with reduction in GFR
- Lactic acidosis
- Myocardial ischemia
- Necrotizing fasciitis
- Paradoxical bronchospasm
- Pulmonary edema
- Supraventricular tachycardia
- Ventricular arrhythmias
- Ventricular fibrillation
- Ventricular premature beats
Less Severe
- Acute confusion
- Agitation
- Apprehension
- Blanching of skin
- Drowsy
- Hyperhidrosis
- Hypesthesia
- Injection site sequelae
- Memory impairment
- Nausea
- Oliguria
- Panic disorder
- Paresthesia
- Pilomotor abnormalities
- Vomiting
- Xerostomia
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Epinephrine (Epipen)
Hold leg firmly with younger child during administration. Use weight based dosing (0.01mg/kg). If weight is <30kg, use lower strength solution (0.15mg).
- 1 Day – 18 Years
- Hold leg firmly with younger child during administration. Use weight based dosing (0.01mg/kg). If weight is <30kg, use lower strength solution (0.15mg).
Epinephrine
- Severity Level:
2
- Additional Notes: Insufficient human data available
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Epinephrine
Poor oral bioavailability and short half-life; unlikely to affect infant.
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Poor oral bioavailability and short half-life; unlikely to affect infant. |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Epinephrine
Cardiovascular-Increased risk of cardiovascular side effects: tachycardia, Neuro/Psych-Increased risk of neuropsychological adverse events.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | N | Y | Y | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
| Anaphylaxis | |
| T78.0 | Anaphylactic reaction due to food |
| T78.00 | Anaphylactic reaction due to unspecified food |
| T78.00xA | Anaphylactic reaction due to unspecified food, initial encounter |
| T78.01 | Anaphylactic reaction due to peanuts |
| T78.01xA | Anaphylactic reaction due to peanuts, initial encounter |
| T78.02 | Anaphylactic reaction due to shellfish (crustaceans) |
| T78.02xA | Anaphylactic reaction due to shellfish (crustaceans), initial encounter |
| T78.03 | Anaphylactic reaction due to other fish |
| T78.03xA | Anaphylactic reaction due to other fish, initial encounter |
| T78.04 | Anaphylactic reaction due to fruits and vegetables |
| T78.04xA | Anaphylactic reaction due to fruits and vegetables, initial encounter |
| T78.05 | Anaphylactic reaction due to tree nuts and seeds |
| T78.05xA | Anaphylactic reaction due to tree nuts and seeds, initial encounter |
| T78.06 | Anaphylactic reaction due to food additives |
| T78.06xA | Anaphylactic reaction due to food additives, initial encounter |
| T78.07 | Anaphylactic reaction due to milk and dairy products |
| T78.07xA | Anaphylactic reaction due to milk and dairy products, initial encounter |
| T78.08 | Anaphylactic reaction due to eggs |
| T78.08xA | Anaphylactic reaction due to eggs, initial encounter |
| T78.09 | Anaphylactic reaction due to other food products |
| T78.09xA | Anaphylactic reaction due to other food products, initial encounter |
| T78.2 | Anaphylactic shock, unspecified |
| T78.2xxA | Anaphylactic shock, unspecified, initial encounter |
| T80.5 | Anaphylactic reaction due to serum |
| T80.51 | Anaphylactic reaction due to administration of blood and blood products |
| T80.51xA | Anaphylactic reaction due to administration of blood and blood products, initial encounter |
| T80.52 | Anaphylactic reaction due to vaccination |
| T80.52xA | Anaphylactic reaction due to vaccination, initial encounter |
| T80.59 | Anaphylactic reaction due to other serum |
| T80.59xA | Anaphylactic reaction due to other serum, initial encounter |
| T88.6 | Anaphylactic reaction due to adverse effect of correct drug or medicament properly administered |
| T88.6xxA | Anaphylactic reaction due to adverse effect of correct drug or medicament properly administered, initial encounter |
| 0-9 | A-Z |
|---|---|
| T78.0 | Anaphylactic reaction due to food |
| T78.00 | Anaphylactic reaction due to unspecified food |
| T78.00xA | Anaphylactic reaction due to unspecified food, initial encounter |
| T78.01 | Anaphylactic reaction due to peanuts |
| T78.01xA | Anaphylactic reaction due to peanuts, initial encounter |
| T78.02 | Anaphylactic reaction due to shellfish (crustaceans) |
| T78.02xA | Anaphylactic reaction due to shellfish (crustaceans), initial encounter |
| T78.03 | Anaphylactic reaction due to other fish |
| T78.03xA | Anaphylactic reaction due to other fish, initial encounter |
| T78.04 | Anaphylactic reaction due to fruits and vegetables |
| T78.04xA | Anaphylactic reaction due to fruits and vegetables, initial encounter |
| T78.05 | Anaphylactic reaction due to tree nuts and seeds |
| T78.05xA | Anaphylactic reaction due to tree nuts and seeds, initial encounter |
| T78.06 | Anaphylactic reaction due to food additives |
| T78.06xA | Anaphylactic reaction due to food additives, initial encounter |
| T78.07 | Anaphylactic reaction due to milk and dairy products |
| T78.07xA | Anaphylactic reaction due to milk and dairy products, initial encounter |
| T78.08 | Anaphylactic reaction due to eggs |
| T78.08xA | Anaphylactic reaction due to eggs, initial encounter |
| T78.09 | Anaphylactic reaction due to other food products |
| T78.09xA | Anaphylactic reaction due to other food products, initial encounter |
| T78.2 | Anaphylactic shock, unspecified |
| T78.2xxA | Anaphylactic shock, unspecified, initial encounter |
| T80.5 | Anaphylactic reaction due to serum |
| T80.51 | Anaphylactic reaction due to administration of blood and blood products |
| T80.51xA | Anaphylactic reaction due to administration of blood and blood products, initial encounter |
| T80.52 | Anaphylactic reaction due to vaccination |
| T80.52xA | Anaphylactic reaction due to vaccination, initial encounter |
| T80.59 | Anaphylactic reaction due to other serum |
| T80.59xA | Anaphylactic reaction due to other serum, initial encounter |
| T88.6 | Anaphylactic reaction due to adverse effect of correct drug or medicament properly administered |
| T88.6xxA | Anaphylactic reaction due to adverse effect of correct drug or medicament properly administered, initial encounter |
Formulary Reference Tool