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SENSIPAR (CINACALCET HCL)
- Hyperparathyroidism secondary to CRF with dialysis
- Hypercalcemia due to primary hyperparathyroidism
- Parathyroid carcinoma with hypercalcemia
30 mg tablet
- 1 tablet (30 mg) by oral route once daily with food
60 mg tablet
- 1 tablet (60 mg) by oral route once daily with food
90 mg tablet
- 1 tablet (90 mg) by oral route once daily with food
30 mg tablet
- 1 tablet (30 mg) by oral route once daily with food
60 mg tablet
- 1 tablet (60 mg) by oral route once daily with food
90 mg tablet
- 1 tablet (90 mg) by oral route once daily with food
cinacalcet 30 mg tablet
- 1 tablet (30 mg) by oral route once daily with food
cinacalcet 60 mg tablet
- 1 tablet (60 mg) by oral route once daily with food
cinacalcet 90 mg tablet
- 1 tablet (90 mg) by oral route once daily with food
Hypercalcemia due to primary hyperparathyroidism
- 1 tablet (30 mg) by oral route 2 times per day with food
- 2 tablets (60 mg) by oral route 2 times per day with food
- 1 tablet (60 mg) by oral route 2 times per day with food
- 1 tablet (90 mg) by oral route 2 times per day with food
- 1 tablet (90 mg) by oral route 3 times per day with food
- 1 tablet (90 mg) by oral route 4 times per day with food
Hyperparathyroidism secondary to CRF with dialysis
- 1 tablet (30 mg) by oral route once daily with food
- 1 tablet (60 mg) by oral route once daily with food
- 2 tablets (60 mg) by oral route once daily with food
- 1 tablet (90 mg) by oral route once daily with food
- 2 tablets (120 mg) by oral route once daily with food
- 2 tablets (180 mg) by oral route once daily with food
Parathyroid carcinoma with hypercalcemia
- 1 tablet (30 mg) by oral route 2 times per day with food
- 2 tablets (60 mg) by oral route 2 times per day with food
- 1 tablet (60 mg) by oral route 2 times per day with food
- 1 tablet (90 mg) by oral route 2 times per day with food
- 1 tablet (90 mg) by oral route 3 times per day with food
- 1 tablet (90 mg) by oral route 4 times per day with food
- None
Contraindicated
- atomoxetine
- Brintellix
- Soltamox
- Strattera
- tamoxifen
- vortioxetine
Severe
Moderate
- Conzip
- desipramine
- ketoconazole
- Norpramin
- Synapryn
- tramadol
- tramadol-acetaminophen
- tramadol-glucosamine
- Ultracet
- Ultram
- Ultram Er
- Congenital long QT syndrome
Contraindicated
- Esophagitis
- Hypocalcemia
- Peptic ulcer
- Prolonged QT interval
- Seizure disorder
Severe
Moderate
- Adynamic bone disease
- Chronic heart failure
- Disease of liver
- Hypophosphatemia
- Hypotension
SENSIPAR (CINACALCET HCL)
- Hyperparathyroidism secondary to CRF with dialysis
- Hypercalcemia due to primary hyperparathyroidism
- Parathyroid carcinoma with hypercalcemia
- None
- Diarrhea
- Dizziness
- Myalgias
- Nausea
- Paresthesia
- Vomiting
More Frequent
Severe
Less Severe
- Dehydration
- Hyperkalemia
- Hypertension
- Hypocalcemia
- Non-cardiac chest pain
- Seizure disorder
- Acute abdominal pain
- Anorexia
- Back pain
- Constipation
- Dyspepsia
- Dyspnea
- General weakness
- Headache disorder
- Muscle spasm
- Upper abdominal pain
- Upper respiratory infection
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Adynamic bone disease
- Angioedema
- Cardiac arrhythmia
- Fracture
- Gastrointestinal hemorrhage
- Hypotension
- Worsening of chronic heart failure
Less Severe
- Skin rash
- Urticaria
Contraindicated
None
Severe Precaution
Cinacalcet
Risk of severe hypocalcemia. Not indicated in pediatrics per manufacturer.
- 1 Day – 18 Years
- Risk of severe hypocalcemia. Not indicated in pediatrics per manufacturer.
Management or Monitoring Precaution
None
Cinacalcet
- Severity Level:
2
- Additional Notes: Insufficient human data available.
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Cinacalcet
Insufficient human data
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient human data |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| Hypercalcemia due to primary hyperparathyroidism | |
| E21.0 | Primary hyperparathyroidism |
| E83.52 | Hypercalcemia |
| Hyperparathyroidism secondary to CRF with dialysis | |
| N25.81 | Secondary hyperparathyroidism of renal origin |
| Parathyroid carcinoma with hypercalcemia | |
| C75.0 | Malignant neoplasm of parathyroid gland |
| 0-9 | A-Z |
|---|---|
| C75.0 | Malignant neoplasm of parathyroid gland |
| E21.0 | Primary hyperparathyroidism |
| E83.52 | Hypercalcemia |
| N25.81 | Secondary hyperparathyroidism of renal origin |
Formulary Reference Tool