Phenagil (phenylephrine hcl/chlorpheniramine maleate) — GIL PHARM

Allergic rhinitis
Cold symptoms
Nasal congestion
Allergic conjunctivitis
Perennial allergic rhinitis
Rhinorrhea
Seasonal allergic rhinitis
Sneezing
Vasomotor rhinitis
3.5 mg-10 mg tablet
Dosage information is not available

3.5 mg-10 mg tablet
Dosage information is not available

Severe Warnings
Acute hepatitis
Acute pancreatitis
Benign prostatic hyperplasia
Bladder outflow obstruction
Bradycardia
Chronic idiopathic constipation
Coronary artery disease
Gastrointestinal obstruction
Hypertension
Hyperthyroidism
Incomplete AV heart block
Narrow angle glaucoma
Severe arteriosclerotic vascular disease
Stenosing peptic ulcer
Urinary retention
Contraindicated
Arterial thrombosis
Myocardial infarction
Severe uncontrolled hypertension
Ventricular tachycardia
Moderate Warnings
Acidosis
Chronic heart failure
Chronic obstructive pulmonary disease
Hypertension
Hyperthyroidism
Hypoxia
Less Frequent
Severe
None

Less Severe
None
More Frequent
Severe
None

Less Severe
Drowsy
Thick bronchial secretions
Rare / Very Rare
Severe
Blood dyscrasias
Conduction disorder of the heart
Dizziness
Extrasystoles
Hallucinations
Headache disorder
Hyperhidrosis
Insomnia
Nervousness
Pallor
Seizure disorder
Tachyarrhythmia
Tremors

Less Severe
Abdominal pain with cramps
Anorexia
Blurred vision
Diarrhea
Dizziness
Dry nose
Dry throat
Dysuria
Excitement
Headache disorder
Hyperhidrosis
Impaired cognition
Insomnia
Irritability
Nervousness
Nightmares
Palpitations
Pruritus of skin
Skin photosensitivity
Skin rash
Tachyarrhythmia
Tinnitus
Tremors
Urinary retention
Urticaria
Vertigo
Visual changes
Xerostomia
More information
Contraindicated
Chlorpheniramine
1 Day – 2 Years
Possible paradoxical CNS excitation. Seizure risk in newborns.
Phenylephrine (Oral,Rectal)
1 Day – 6 Years
Risk of CNS excitation. Do not use age <6 years without clinician consult.

Severe Precaution
Chlorpheniramine
2 Years – 6 Years
Not recommended in children under 6 years unless clinician consultation.

Management or Monitoring Precaution
None
Chlorpheniramine
Severity Level: 2
Additional Notes: Insufficient data available; neonate risk of seizures;avoid during 3rd trimester

Phenylephrine
Severity Level: C
Additional Notes: Evidence for malformations; can reduce uterine blood flow causing fetal hypoxia

More information
Contraindicated
None

Precaution Exists
Chlorpheniramine
GeneralExcretion PotentialEffect on InfantNotes
Evaluate use carefullyUnknownNot known; no or inclusive dataInsufficient data available; may cause sedation and inhibit lactation
Phenylephrine
GeneralExcretion PotentialEffect on InfantNotes
Evaluate use carefullyExcretedNot known; no or inclusive dataOral bioavailability low; infant exposure may be minimal

No Known Risk
None
More information
Contraindicated
None

Precaution Exists
Chlorpheniramine
Neuro/Psych-Anticholinergic effects may cause sedation, worsen cognitive impairment and increase fall risk. Non-sedating antihistamine preferred. Gastrointestinal-May cause or worsen pre-existing constipation. Genitourinary-Best avoided in patients with urinary retention from any cause.
Organ / SystemHEPRENCARDENDONEURO / PSYCHPULM
Increased Risk / Adverse EffectsNNNNYN
BEERS: Y   HEDIS: Y   STOPP: Y

Phenylephrine
Cardiovascular-Elderly are more sensitive to tachycardia and hypertensive effects. May exacerbate symptomatic coronary insufficiency. Genitourinary-May cause urinary retention. Neuro/Psych-May worsen cognitive impairment in some elderly with dementia. Insomnia risk.
Organ / SystemHEPRENCARDENDONEURO / PSYCHPULM
Increased Risk / Adverse EffectsNNYNYN
BEERS: Y   HEDIS: Y   STOPP: N

No Known Risk
None
Allergic conjunctivitis
H10.1Acute atopic conjunctivitis
H10.10Acute atopic conjunctivitis, unspecified eye
H10.11Acute atopic conjunctivitis, right eye
H10.12Acute atopic conjunctivitis, left eye
H10.13Acute atopic conjunctivitis, bilateral
H10.44Vernal conjunctivitis
H10.45Other chronic allergic conjunctivitis
H16.26Vernal keratoconjunctivitis, with limbar and corneal involvement
H16.261Vernal keratoconjunctivitis, with limbar and corneal involvement, right eye
H16.262Vernal keratoconjunctivitis, with limbar and corneal involvement, left eye
H16.263Vernal keratoconjunctivitis, with limbar and corneal involvement, bilateral
H16.269Vernal keratoconjunctivitis, with limbar and corneal involvement, unspecified eye
Allergic rhinitis
J30Vasomotor and allergic rhinitis
J30.0Vasomotor rhinitis
J30.1Allergic rhinitis due to pollen
J30.2Other seasonal allergic rhinitis
J30.5Allergic rhinitis due to food
J30.8Other allergic rhinitis
J30.81Allergic rhinitis due to animal (cat) (dog) hair and dander
J30.89Other allergic rhinitis
J30.9Allergic rhinitis, unspecified
J31.0Chronic rhinitis
Nasal congestion
R09.81Nasal congestion
Rhinorrhea
J31.0Chronic rhinitis
R09.82Postnasal drip
Seasonal allergic rhinitis
J30.1Allergic rhinitis due to pollen
J30.2Other seasonal allergic rhinitis
0-9 A-Z
H10.1 Acute atopic conjunctivitis
H10.10 Acute atopic conjunctivitis, unspecified eye
H10.11 Acute atopic conjunctivitis, right eye
H10.12 Acute atopic conjunctivitis, left eye
H10.13 Acute atopic conjunctivitis, bilateral
H10.44 Vernal conjunctivitis
H10.45 Other chronic allergic conjunctivitis
H16.26 Vernal keratoconjunctivitis, with limbar and corneal involvement
H16.261 Vernal keratoconjunctivitis, with limbar and corneal involvement, right eye
H16.262 Vernal keratoconjunctivitis, with limbar and corneal involvement, left eye
H16.263 Vernal keratoconjunctivitis, with limbar and corneal involvement, bilateral
H16.269 Vernal keratoconjunctivitis, with limbar and corneal involvement, unspecified eye
J30 Vasomotor and allergic rhinitis
J30.0 Vasomotor rhinitis
J30.1 Allergic rhinitis due to pollen
J30.1 Allergic rhinitis due to pollen
J30.2 Other seasonal allergic rhinitis
J30.2 Other seasonal allergic rhinitis
J30.5 Allergic rhinitis due to food
J30.8 Other allergic rhinitis
J30.81 Allergic rhinitis due to animal (cat) (dog) hair and dander
J30.89 Other allergic rhinitis
J30.9 Allergic rhinitis, unspecified
J31.0 Chronic rhinitis
J31.0 Chronic rhinitis
R09.81 Nasal congestion
R09.82 Postnasal drip

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Diagnosis codes are provided for reference only. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatement.