Phenagil (phenylephrine hcl/chlorpheniramine maleate) — GIL PHARM

Allergic rhinitis
Cold symptoms
Nasal congestion
Allergic conjunctivitis
Atopic rhinitis
Rhinorrhea
Seasonal allergic rhinitis
Sneezing
Vasomotor rhinitis
3.5 mg-10 mg tablet
Dosage information is not available

Severe Warnings
Acute hepatitis
Acute pancreatitis
Benign prostatic hypertrophy
Bladder outflow obstruction
Bradycardia
Chronic idiopathic constipation
Coronary artery disease
Gastrointestinal obstruction
Hypertension
Hyperthyroidism
Incomplete AV heart block
Narrow angle glaucoma
Severe arteriosclerotic vascular disease
Stenosing peptic ulcer
Urinary retention
Contraindicated
Arterial thrombosis
Myocardial infarction
Severe uncontrolled hypertension
Ventricular tachycardia
Moderate Warnings
Acidosis
Chronic heart failure
Chronic obstructive pulmonary disease
Hypertension
Hyperthyroidism
Hypoxia
Less Frequent
Severe
None

Less Severe
None
More Frequent
Severe
None

Less Severe
Drowsy
Thick bronchial secretions
Rare / Very Rare
Severe
Allergic reactions
Blood dyscrasias
Conduction disorder of the heart
Dizziness
Extrasystoles
Hallucinations
Headache disorder
Hyperhidrosis
Insomnia
Nervousness
Pallor
Tachyarrhythmia
Tonic clonic seizure
Tremors

Less Severe
Abdominal pain with cramps
Anorexia
Blurred vision
Dizziness
Dry nose
Dry throat
Dysuria
Excitement
Headache disorder
Hyperhidrosis
Impaired cognition
Nervousness
Nightmares
Pruritus of skin
Skin photosensitivity
Skin rash
Tachyarrhythmia
Tinnitus
Tremors
Urticaria
Visual changes
Xerostomia
More information
Contraindicated
Chlorpheniramine
1 Day – 2 Years
Possible paradoxical CNS excitation. Seizure risk in newborns.
Phenylephrine (Oral,Rectal)
1 Day – 6 Years
Risk of CNS excitation. Do not use age <6 years without clinician consult.

Severe Precaution
Chlorpheniramine
2 Years – 6 Years
Not recommended in children under 6 years unless clinician consultation.

Management or Monitoring Precaution
None
Chlorpheniramine
Severity Level: 2
Additional Notes: Insufficient data available; neonate risk of seizures;avoid during 3rd trimester

Phenylephrine
Severity Level: C
Additional Notes: Evidence for malformations; can reduce uterine blood flow causing fetal hypoxia

More information
Contraindicated
None

Precaution Exists
Chlorpheniramine
GeneralExcretion PotentialEffect on InfantNotes
Evaluate use carefullyUnknownNot known; no or inclusive dataInsufficient data available; may cause sedation and inhibit lactation
Phenylephrine
GeneralExcretion PotentialEffect on InfantNotes
Evaluate use carefullyExcretedNot known; no or inclusive dataOral bioavailability low; infant exposure may be minimal

No Known Risk
None
More information
Contraindicated
None

Precaution Exists
Chlorpheniramine
Neuro/Psych-Anticholinergic effects may cause sedation, worsen cognitive impairment and increase fall risk. Non-sedating antihistamine preferred. Gastrointestinal-May cause or worsen pre-existing constipation. Genitourinary-Best avoided in patients with urinary retention from any cause.
Organ / SystemHEPRENCARDENDONEURO / PSYCHPULM
Increased Risk / Adverse EffectsNNNNYN
BEERS: Y   HEDIS: Y   STOPP: Y

Phenylephrine
Cardiovascular-Elderly are more sensitive to tachycardia and hypertensive effects. May exacerbate symptomatic coronary insufficiency. Genitourinary-May cause urinary retention. Neuro/Psych-May worsen cognitive impairment in some elderly with dementia. Insomnia risk.
Organ / SystemHEPRENCARDENDONEURO / PSYCHPULM
Increased Risk / Adverse EffectsNNYNYN
BEERS: Y   HEDIS: Y   STOPP: N

No Known Risk
None
Allergic conjunctivitis
372.14Chronic allergic conjunctivitis not elsewhere classified
372.3Conjunctivitis not elsewhere classified and not otherwise specified
372.30Conjunctivitis not otherwise specified
372.39Conjunctivitis not elsewhere classified
Allergic rhinitis
477Allergic rhinitis
477.0Rhinitis due to pollen
477.1Allergic rhinitis due to food
477.2Allergic rhinitis due to animal (cat, dog) hair and dander
477.8Allergic rhinitis not elsewhere classified
477.9Allergic rhinitis not otherwise specified
Atopic rhinitis
477.9Allergic rhinitis not otherwise specified
Cold symptoms
460Acute nasopharyngitis
Nasal congestion
478.1Other diseases of nasal cavity and sinuses
478.19Other disease of nasal cavity and sinuses
Rhinorrhea
478.1Other diseases of nasal cavity and sinuses
478.19Other disease of nasal cavity and sinuses
Seasonal allergic rhinitis
477.9Allergic rhinitis not otherwise specified
Sneezing
784.9Other symptom involving head and neck
784.99Other symptoms involving head and neck
Vasomotor rhinitis
477.9Allergic rhinitis not otherwise specified
0-9 A-Z
372.14 Chronic allergic conjunctivitis not elsewhere classified
372.3 Conjunctivitis not elsewhere classified and not otherwise specified
372.30 Conjunctivitis not otherwise specified
372.39 Conjunctivitis not elsewhere classified
460 Acute nasopharyngitis
477 Allergic rhinitis
477.0 Rhinitis due to pollen
477.1 Allergic rhinitis due to food
477.2 Allergic rhinitis due to animal (cat, dog) hair and dander
477.8 Allergic rhinitis not elsewhere classified
477.9 Allergic rhinitis not otherwise specified
477.9 Allergic rhinitis not otherwise specified
477.9 Allergic rhinitis not otherwise specified
477.9 Allergic rhinitis not otherwise specified
478.1 Other diseases of nasal cavity and sinuses
478.1 Other diseases of nasal cavity and sinuses
478.19 Other disease of nasal cavity and sinuses
478.19 Other disease of nasal cavity and sinuses
784.9 Other symptom involving head and neck
784.99 Other symptoms involving head and neck

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Diagnosis codes are provided for reference only. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatement.